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D.A. SPANDIDOS - PUBLICATIONS

1. Taylor-Papadimitriou J, SPANDIDOS DA and Georgatsos JG: An endonuclease activity associated with preparations of chick interferon. Biochemical and Biophysical Research Communications 43: 149-155, 1971.
2. SPANDIDOS DA and Graham AF: Complementation of reovirus by its mutants. Journal of Virology 15: 954-963, 1975.
3. SPANDIDOS DA and Graham AF: Complementation between temperature- sensitive and deletion mutants of reovirus. Journal of Virology 16: 1444-1452, 1975.
4. SPANDIDOS DA, Krystal G and Graham AF: Regulated transcription of the genomes of defective virions and temperature-sensitive mutants of reovirus. Journal of Virology 18: 7-19, 1976.
5. SPANDIDOS DA and Graham AF: Recombination between temperature-sensitive and deletion mutants of reovirus. Journal of Virology 18: 117-123, 1976.
6. SPANDIDOS DA and Graham AF: Infectious center assay for complementation and recombination between mutants of reovirus. Journal of Virology 18: 1151-1154, 1976.
7. SPANDIDOS DA and Graham AF: Physical and chemical characterization of an avian reovirus. Journal of Virology 19: 968-976, 1976.
8. SPANDIDOS DA and Graham AF: Non-permissive infection of L cells by avian reovirus: Restricted transcription of the viral genome. Journal of Virology 19: 977-984, 1976.
9. SPANDIDOS DA and Graham AF: Generation of defective virus after infection of newbons rats with reovirus. Journal of Virology 20: 234-247, 1976.
10. SPANDIDOS DA and Siminovitch L: Transfer of codominant markers by isolated metaphase chromosomes in Chinese hamster ovary cells. Proceedings of the National Academy of Science USA 74: 3480-3484, 1977.
11. SPANDIDOS DA and Siminovitch L: Linkage of markers controlling consecutive biochemical steps in CHO cells as demonstrated by chromosome transfer. Cell 12: 235-242, 1977.
12. SPANDIDOS DA and Siminovitch L: Transfer of anchorage independence by isolated metaphase chromosomes in hamster cells. Cell 12: 675-682, 1977.
13. SPANDIDOS DA and Siminovitch L: Genetic analysis of chromosome transfer in hamster cells. Brookhaven Symposium on Biology 29: 127-134, 1977.
14. SPANDIDOS DA and Siminovitch L: Transfer of the marker for the morphologically transformed phenotype by isolated chromosomes in hamsters cells. Nature 271: 259-261, 1978.
15. SPANDIDOS DA and Siminovitch L: The relationship between transformation and somatic mutation in human and Chinese hamster cells. Cell 13: 651-662, 1978.
16. SPANDIDOS DA, Ramandanis G, Garas J and Kottaridis SD: Serum deoxyribonucleases in patients with breast cancer. European Journal of Cancer 16: 1615-1619, 1980.
17. SPANDIDOS DA and Stathopoulos G: Serum deoxyribonucleases as a biological marker in cancer patients. In: Human Cancer its Characterization and Treatment. Ed. W Davies, KR Harrap and G Stathopoulos. Excepta Medica 5: 68-73, 1980.
18. Kalogeropoulou P, Bonikos D and SPANDIDOS DA: Deoxyribonuclease levels in benign and malignant neoplasms of female reproductive system. In: Human Cancer, its Characterization and Treatment. (Ed). W Davies, KR Harrap and G Stathopoulos. Excepta Medica 5: 74-77, 1980.
19. Agnantis N, Ramandanis G, Garas J and SPANDIDOS DA: Comparison between DNase levels and histological parameters in patients with benign and malignant breast disease. In: Diagnosis and Treatment of Breast Cancer: International Aspects. Williams and Wilkins. Baltimore, USA, pp89-93, 1981.
20. Scully C, SPANDIDOS DA, Ward-Booth P, McGregor IA and Boyle P: Serum alkaline deoxyribonuclease in oral cancer and premalignant lesions. Biomedicine 35: 179-180, 1981.
21. SPANDIDOS DA, Harrison PR and Paul J: Transfer and expression of Herpes Simplex virus thymidine kinase and human globin genes in mammalian cells studied by spot hybridization assays. Bioscience Reports 1: 911-920, 1981.
22. Ramandanis G, Agnantis N, Garas J and SPANDIDOS DA: Correlation between serum and tissue deoxyribonuclease levels in breast cancer patients. Anticancer Research 2: 213-216, 1982.
23. Rigas A and SPANDIDOS DA: Statistical analysis of acid and alkaline DNAase levels found in the serum and biopsies of breast cancer patients. Anticancer Research 2: 216-218, 1982.
24. SPANDIDOS DA and Paul J: Transfer of human globin genes to erythroleukaemic mouse cells. EMBO Journal 1: 15-20, 1982.
25. SPANDIDOS DA, Harrison PR and Paul J: Replication and amplification of recombinant plasmid molecules as extra chromosomal elements in transformed mammalian cells. Experimental Cell Research 141: 149-158, 1982.
26. Paul J and SPANDIDOS DA: Expression of the human epsilon globin gene in mouse erythroleukaemic cells transformed with recombinants between it and a bacterial plasmid vector. In: Stability and Switching in Cellular Differentiation. Advances in Experimental Medicine and Biology, vol. 158. Ed. by RM Clayton and DES Truman. Plenum Press, New York, pp89-92, 1982.
27. Paul J, Allan M, Grindlay J and SPANDIDOS DA: The human epsilon globin gene-a paradigm for erythroid differentiation. In: Biochemistry of Differentiation and Morphogenesis. 33 Coloquium Mosbach, Springer-Verlag, Berlin Heidelberg Ed. by L Jaenicke, pp142-153, 1982.
28. Gilmour RS, Gow JW and SPANDIDOS DA: In vivo assembly of regularly spaced nucleosomes on mouse §-maj-globin DNA cloned in an SV40 recombinant. Bioscience Reports 2: 1031-1040, 1982.
29. Lykourinas M, Constantinidis C, SPANDIDOS DA, Manthopoulos A and Dimopoulos C: The role of acid and alkaline DNases as tumor markers in cancer of the genitourinary tract. Urological Research 10: 67-70, 1982.
30. SPANDIDOS DA: Cellular oncogenes, mutations and cancer. Anticancer Research 3: 121-125, 1983.
31. Campo MS and SPANDIDOS DA: Molecularly cloned bovine papilloma-virus DNA transforms mouse fibroblasts in vitro. Journal of General Virology 64: 549-557, 1983.
32. Campo MS, SPANDIDOS DA, Lang J and Wilkie NM: Transcriptional control signals in the genome of bovine papillomavirus type 1. Nature 303: 77-80, 1983.
33. SPANDIDOS DA and Wilkie NM: Host-specificities of papillomavirus, Moloney murine sarcoma virus and Simian virus enhancer sequences. EMBO Journal 2: 1193-1199, 1983.
34. Lang JC, Wilkie NM and SPANDIDOS DA: Characterization of eukaryotic transcriptional control signals by assay of herpes simplex virus type 1 thymidine kinase. Journal of General Virology 64: 2679-2696, 1983.
35. SPANDIDOS DA: Expression of the human beta globin gene and 5'-deletion mutants in erythroleukemic mouse cells studied by DNA mediated gene transfer. Anticancer Research 3: 409-416, 1983.
36. Lang JC, SPANDIDOS DA and Wilkie NM: Regulation of the HSV-1 immediate-early gene is mediated through an enhancer. EMBO Journal 3: 389-395, 1984.
37. SPANDIDOS DA and Wilkie NM: Expression of exogenous DNA in mammalian cells. In: In vitro Transcription and Translation-A Practical Approach. Ed. by B.D. Hames and S.J.Higgins. IRL Press. Oxford, pp1-48, 1984.
38. SPANDIDOS DA and Wilkie NM: Tumorigenic conversion of early passage rodent cells can be achieved with a single activated human oncogene. In: Cancer Cells. Oncogenes and Viral Genes. Ed. by GF Vande Woude, AJ Levine, WC Toppand, JD Watson. Cold Spring Harbor Lab., New York, USA, Vol. 2: 495-500, 1984.
39. SPANDIDOS DA and Kerr IB: Elevated expression of the human ras oncogene family in premalignant and malignant tumours of the colorectum. British Journal of Cancer 49: 681-688, 1984.
40. Gilmour RS, SPANDIDOS DA, Vass JK, Gow JW and Paul JA: Negative regulatory sequence near the mouse §-maj-globin gene associated with a region of potential Z-DNA. EMBO Journal 3: 1263-1272, 1984.
41. SPANDIDOS DA and Wilkie NM: Malignant transformation of early passage rodent cells by a single mutated human oncogene. Nature 310: 469-475, 1984.
42. Wilkie NM and SPANDIDOS DA: In vitro malignant transformation of primary cells by active oncogenes. In: UCLA Symposium on Molecular and Cellular Biology, New Series. Genes and Cancer 17: 471-488, 1984.
43. SPANDIDOS DA and Agnantis NJ: Human malignant tumours of the breast, as compared to their respective normal tissue, have elevated expression of the Harvey ras oncogene. Anticancer Research 4: 269-272, 1984.
44. SPANDIDOS DA and Anderson MLM: A tissue-specific transcription enhancer element in the human immunoglobulin ?-chain locus. FEBS Letters 175: 152-158, 1984.
45. SPANDIDOS DA: Transfer of human globin genes to erythroleukaemic human cells. Molecular Biology and Medicine 2: 167-175, 1984.
46. SPANDIDOS DA, Kam EY and Balfour R: Transformation of mammalian cells by iontophoretic pricking and iontophoretic micro-injection. European Journal of Cell Biology 37: 234-239, 1985.
47. SPANDIDOS DA, Lammothe A and Field JK: Multiple transcriptional activation of cellular oncogenes in the human head and neck solid tumours. Anticancer Research 5: 221-224, 1985.
48. Paul J, Allan M, Gilmour S, SPANDIDOS DA, Montague P, Grindlay J, Vass K, Zhu Jing-de and Gow J: Distant sequences which regulate globin genes. In: Experimental Approaches for the study of Hemoglobin Switching. (Ed). G Stamatoyanopoulos, Alan R Liss, Inc. pp29-48, 1985.
49. Pragnell IB, SPANDIDOS DA and Wilkie NM: Consequences of altered oncogene expression in rodent cells. Proceedings of the Royal Society of London, UK. B226: 107-119, 1985.
50. SPANDIDOS DA, Freshney M and Wilkie NM: Heterogeneity of cell lines derived after transformation of early passage rodent cells by the Ha-ras1 human oncogene. Anticancer Research 5: 387-392, 1985.
51. Williams ARW, Piris J, SPANDIDOS DA and Wyllie AH: Immunohistochemical detection of the ras oncogene p21 product in an experimental tumour and in human colorectal neoplasms. British Journal of Cancer 52: 687-693, 1985.
52. SPANDIDOS DA: Mechanisms of carcinogenesis: the role of oncogenes, transcriptional enhancers and growth factors. Anticancer Research 5: 485-498, 1985.
53. SPANDIDOS DA and Dimitrov T: High expression levels of ras p21 protein in normal mouse heart tissues. Bioscience Reports 5: 1035-1039, 1985.
54. Agnantis NJ, Parissi P, Anagnostakis D and SPANDIDOS DA: Comparative study of Harvey ras oncogene expression with conventional clinicopathologic parameters of breast cancer. Oncology 43: 366-369, 1986.
55. Kerr IB, SPANDIDOS DA, Finlay IG, Lee FE and McArdle CS: The relation of ras family oncogene expression to conventional staging criteria and clinical outcome in colorectal carcinoma. British Journal of Cancer 53: 231-235, 1986.
56. Agnantis NJ and SPANDIDOS DA: Expression of the human Harvey ras oncogene in breast cancer. In: Breast Cancer: Origins, Detection and Treatment. MA Rich, JC Hager and J Taylor-Papadimitriou (Eds). Martinus Nijhoff Publishing, Boston, USA, pp190-194, 1986.
57. SPANDIDOS DA: The human T24 Ha-ras1 oncogene: A study of the effects of overexpression of the mutated ras gene product in rodent cells. Anticancer Research 6: 259-262, 1986.
58. SPANDIDOS DA, Dimitrov T and Kam EY: A radio-immunocytological method for the rapid detection of ras oncogene p21 protein in mammalian cells. Bioscience Reports 6: 375-379, 1986.
59. Lang JC and SPANDIDOS DA: The structure and function of eukaryotic enhancer elements and their role in oncogenesis. Anticancer Research 6: 437-450, 1986.
60. SPANDIDOS DA and Riggio M: Polyoma virus middle T gene can trigger malignant transformation of early passage rodent cells. Journal of General Virology 67: 793-799, 1986.
61. Anderson MLM, McColl LA and SPANDIDOS DA: The effect of human IgG ? fragments on gene expression in transfected mouse fibroblasts. Anticancer Research 6: 663-666, 1986.
62. Field JK, Lamothe A and SPANDIDOS DA: Clinical relevance of oncogene expression in head and neck tumours. Anticancer Research 6: 595-600, 1986.
63. SPANDIDOS DA and Riggio M: Promoter and enhancer-like activity at the 5' end of normal and T24 Ha-ras1 genes. FEBS Letters 203: 169-174, 1986.
64. Agnantis NJ, Petraki C, Markoulatos P and SPANDIDOS DA: Immunohistochemical study of the ras oncogene expression in human breast lesions. Anticancer Research 6: 1157-1160, 1986.
65. Robinson A, Williams ARW, Piris J, SPANDIDOS DA and Wyllie AH: Evaluation of a monoclonal antibody to ras peptide, claimed to bind preferentially to cells of infiltrating carcinomas. British Journal of Cancer 54: 877-883, 1986.
66. SPANDIDOS DA: Review-Hypothesis. A unified theory for the development of cancer. Bioscience Reports 6: 691-708, 1986.
67. Gambari R and SPANDIDOS DA: Chinese hamster lung cells transformed with the human HA-RAS-1 oncogene: azacytidine mediated induction of adipogenic conversion. Cell Biology International Reports 10: 173, 1986.
68. Manolagas SC, Provvedini DM, Murray EJ, Murray SS, Tsonis P and SPANDIDOS DA: Association between the expression of the receptor protein for 1,25 dihydroxyvitamin D3. Proceedings of the National Academy of Sciences, USA, 84: 856-860, 1987.
69. Agnantis NJ, Pintzas A, Kakkanas A, Markoulatos P and SPANDIDOS DA: Expression of the ras oncogene p21 protein in human breast tumors and in several benign conditions using the Y13-259 monoclonal antibody. In: Fundamental Problems in Breast Cancer. AHG Paterson and P Lee (Eds). Martinus Nijhoff Publishing, Boston, USA, pp323-325, 1987.
70. SPANDIDOS DA and Anderson MLM: A study of mechanisms of carcinogenesis by gene transfer of oncogenes into mammalian cells. Mutation Research 185: 271-291, 1987.
71. SPANDIDOS DA: Electric field mediated-gene transfer (electroporation) into mouse Friend and human K562 erythroleukemic cells. Gene Analysis Techniques 40: 50-56, 1987.
72. SPANDIDOS DA and Holmes L: Transcriptional enhancer activity in the variable tandem repeat DNA sequences of the human Ha-ras1 gene. FEBS Letters 218: 41-46, 1987.
73. Field JK and SPANDIDOS DA: Expression of oncogenes in human tumors with special reference to the head and neck region. Journal of Oral Pathology 16: 97-107, 1987.
74. Wyllie AH, Rose KA, Morris RG, Steel CM, Foster E and SPANDIDOS DA: Rodent fibroblast tumours expressing human myc and ras genes: Growth, metastasis and endogenous oncogene expression. British Journal of Cancer 56: 251-259, 1987.
75. SPANDIDOS DA: Gene transfer protocol. In: Culture of Animal Cells. RI Freshney (Ed). Alan Liss Inc, pp333-334, 1987.
76. SPANDIDOS DA: Oncogene activation in malignant transformation. A study of H-ras in human breast cancer. Anticancer Research 7: 991-996, 1987.
77. Yiagnisis M and SPANDIDOS DA: Interleukin 3 like activity secreted from human ras or myc transfected rodent cells. Anticancer Research 7: 1293-1297, 1987.
78. SPANDIDOS DA, Pintzas A, Kakkanas A, Yiagnisis M, Mahera H, Patra E and Agnantis NJ: Elevated expression of the myc gene in human benign and malignant breast lesions compared to normal tissue. Anticancer Research 7: 1299-1304, 1987.
79. Williams ARW, Piris J, SPANDIDOS DA and Willie AH: Immunohistochemical detection of the ras oncogene p21 product in an experimental tumour and in human colorectal neoplasms. In: The Year Book of Cancer, Saunders, pp144-146, 1987.
80. SPANDIDOS DA: Ras oncogenes in cell transformation. ISI Atlas of Science: Immunology 1: 1-6, 1988.
81. Nastruzzi C, Feriotto G, SPANDIDOS DA, Anzanel D, Ferroni R, Guarneri M, Barbieri R and Gambari R: Effects of benzamidine derivatives on Ha-RAS-1 mRNA accumulation in a Chinese hamster cell line transformed with the activated human T24 Ha-RAS-1 oncogene. Anticancer Research 8: 269-274, 1988.
82. Agnantis NJ, SPANDIDOS DA, Mahera H, Parissi P, Kakkanas A, Pintzas A and Papacharalampous NX: Immunohistochemical study of ras oncogene expression in endometrial and cervical human lesions. European Journal of Gynaecological Oncology 9: 360-365, 1988.
83. SPANDIDOS DA and Pintzas A: Differential potency and trans-activation of normal and mutant T24 human H-ras1 gene promoters. FEBS Letters 232: 269-274, 1988.
84. SPANDIDOS DA, Pintzas A, Kakkanas A, Yiagnisis M and Agnantis NJ: Quantitative and qualitative changes in oncogene expression during carcinogenesis. In: Breast Cancer: Scientific and Clinical Progress. MA Rich, JC Hager and DM Lopez (Eds). Kluwer Academic Publishers, Boston, USA, pp24-41, 1988.
85. Anderson MLM and SPANDIDOS DA: Onco-suppressor genes and their involvement in cancer. Anticancer Research 8: 873-880, 1988.
86. SPANDIDOS DA, Nichols RAB, Wilkie NM and Pintzas A: Phorbol ester responsible H-ras1 gene promoter contains multiple TPA-inducible/AP-1-binding consensus sequence elements. FEBS Letters 240: 191-195, 1988.
87. Papamichalis G, Francia K, Karahaliou FE, Anastassiades OTh and SPANDIDOS DA: Expression of the c-myc oncoprotein in metaplastic epithelial cells of fibrocystic disease. Anticancer Research 8: 1217-1222, 1988.
88. Papadimitriou K, Yiagnisis M, Tolis G and SPANDIDOS DA: Immunohistochemical analysis of the ras oncogene protein product in human thyroid neoplasms. Anticancer Research 8: 1223-1227, 1988.
89. SPANDIDOS DA: Oncogenes and the molecular basis of breast cancer. In: Mastology '88. L Ioannidou-Muzaka, M Philippakis, PA Angelakis (Eds). Elsevier Science Publishers, B.V. pp51-55, 1988.
90. SPANDIDOS DA and Wilkie NM: The normal human H-ras1 gene can act as onco-suppressor. British Journal of Cancer 58: Suppl.ix, 67-71, 1988.
91. Field JK and SPANDIDOS DA: Expression of oncogenes in human tumours with special reference to the head and neck region. In: The Year Book of Dentistry, Saunders, pp378-380, 1988.
92. SPANDIDOS DA: The effect of exogenous human ras and myc oncogene in morphological differentiation of the rat pheochromocytoma PC12 cells. International Journal of Developmental Neurosciences 7: 1-4, 1989.
93. Nastruzzi C, Feriotto G, SPANDIDOS DA, Ferroni R, Guarneri M, Barbieri R and Gambari R: Inhibition of in vitro tumor cell growth by aromatic polyamidines exhibiting antiproteinase activity. Clinical and Experimental Metastasis 7: 25-39, 1989.
94. SPANDIDOS DA and Anderson MLM: Oncogenes and onco-suppressor genes: their involvement in cancer. Journal of Pathology 157: 1-10, 1989.
95. SPANDIDOS DA, Yiagnisis M and Pintzas A: Human immunodeficiency virus long terminal repeat responds to transformation by the mutant T24 H-ras1 oncogene and it contains multiple AP-1 binding/TPA-inducible consensus sequence elements. Anticancer Research 9: 383-386, 1989.
96. SPANDIDOS DA: Transcriptional regulatory sequences in the H-ras gene. In: Ras Oncogenes. DA Spandidos (Ed). Plenum Publ Corp, pp11-14, 1989.
97. Yiagnisis M, Papadimitrou K and SPANDIDOS DA: Human thyroid neoplasms express ras p21 protein at high levels. In: Ras Oncogenes. DA Spandidos (Ed). Plenum Press, New York and London, pp47-49, 1989.
98. Wyllie AH, Evans I, Morris RG and SPANDIDOS DA: Regulation of the cell death by ras and myc oncogenes. In: Ras oncogenes. DA Spandidos (Ed). Plenum Press, New York and London, pp149-155, 1989.
99. Tiniakos D, SPANDIDOS DA, Kakkanas A, Pintzas A, Pollice L and Tiniakos G: Expression of ras and myc oncogenes in hepatocellular carcinoma and non-neoplastic liver tissues. Anticancer Research 9: 715-722, 1989.
100. Efremidis AP, Agnantis NJ, Patra F, Papadopoulou C and SPANDIDOS DA: Clinical significance of elevated p21 ras oncogene expression in breast cancer patients. Cancer Journal 2: 288-291, 1989.
101. SPANDIDOS DA, Field JK, Agnantis NJ, Evan GI and Moore JP: High levels of c-myc protein in breast tumors determined by a sensitive ELISA assay. Anticancer Research 9: 821-826, 1989.
102. SPANDIDOS DA and Lang JC: Immortalization by truncated myc or ras genes and synergism between myc and ras genes on cell transformation. Anticancer Research 9: 1149-1152, 1989.
103. SPANDIDOS DA and Lang JC: In vitro cell transformation by ras oncogenes. CRC Critical Reviews in Oncogenesis 1: 195-209, 1989.
104. Nastruzzi C, Simoni D, Barbieri R, Feriotto G, Baruldi PG, SPANDIDOS DA, Guarneri M and Gambari R: New synthetic retinoids: Effects on proliferation and differentiation. Anticancer Research 9: 1377-1384, 1989.
105. SPANDIDOS DA, Yiagnisis M, Papadimitriou K and Field JK: Ras, c-myc, and c-erbB-2 oncoprotein expression in human breast carcinomas. Anticancer Research 9: 1385-1394, 1989.
106. Pintzas A and SPANDIDOS DA: Ras p21 oncoprotein is autoregulated and acts as a potential mediator of insulin action in the H-ras1 promoter. Gene Analysis Techniques 6: 125-130, 1989.
107. Field JK, SPANDIDOS DA, Stell PM, Vaughan ED, Evan GI and Moore JP: Elevated expression of the c-myc oncoprotein correlates with poor prognosis in head and neck squamous cell carcinoma. Oncogene 4: 1463-1468, 1989.
108. Karayiannis M, Yiagnisis M, Papadimitriou K and SPANDIDOS DA: Expression of the ras oncoprotein in gastric carcinomas and adjacent mucosa. Anticancer Research 9: 1505-1510, 1989.
109. SPANDIDOS DA and Lang JC: The role of oncogenes and onco-suppressor genes in carcinogenesis. Chinese Journal for Cancer Research 1: 70-74, 1989.
110. SPANDIDOS DA: The role of the ras p21 product in cell transformation. In: Activation of Hormones and Growth Factor Receptors: MN Alexis and CE Sekeris (Eds). Kluwer Academic Publishers, pp63-67, 1990.
111. Field JK and SPANDIDOS DA: The role of ras and myc oncogenes in human solid tumors and their relevance in diagnosis and prognosis. Anticancer Research 10: 1-22, 1990.
112. Gambari R, Barbieri R, Feriotto G, SPANDIDOS DA and Nastruzzi C: Effects of the proteinase inhibitor tetra-p-amidinophenoxyneopentane on in vitro adhesion and invasiveness of tumor cells. Anticancer Research 10: 259-264, 1990.
113. Agnantis NJ, Constantinidou A, Poulios C, Pinztas A, Kakkanas A and SPANDIDOS DA: Immunohistochemical study of the ras oncogene expression in human bladder endoscopy specimens. European Journal of Surgical Oncology 16: 153-160, 1990.
114. SPANDIDOS DA: Ras oncogenes in multistep carcinogenesis. In: Oncogenesis: Oncogenes in Signal Transduction and Cell Proliferation. TS Papas (Ed). Portofolio Publ Co, pp93-96, 1990.
115. Agnantis NJ, Mahera H, Maounis N, Papanicolaou A and SPANDIDOS DA: Ras p21 oncoprotein expression in human cervical intraepithelial neoplasias and other benign conditions of the uterine cervix. In: Oncogenesis: Oncogenes in Signal Transduction and Cell Proliferation. TS Papas (Ed). Portofolio Publ Co, pp97-101, 1990.
116. Koutselini H, Kappatou G, Yiagnisis M, Field JK and SPANDIDOS DA: Immunocytochemichal study of RAS oncoprotein in cytologic specimens of primary lung tumors. Anticancer Research 10: 597-604, 1990.
117. Gosney JR, Field JK, Gosney MA, Lye MDW, SPANDIDOS DA and Butt SA: C-myc oncoprotein in bronchial carcinoma: expression in all major morphological types. Anticancer Research 10: 623-628, 1990.
118. Giacomini P, Gambari R, Barbieri R, Nastruzzi C,Fraioli R, SPANDIDOS DA, Fisher PB and Natali PG: Recombinant immune interferon down-regulates Ha-ras-1 proto-oncogene products in a human melanoma cell line. Anticancer Research 10: 629-636, 1990.
119. Kakkanas A and SPANDIDOS DA: In vitro and in vivo onco-suppressor activity of normal cells on cells transformed with the H-ras1 oncogene. In Vivo 4: 109-114, 1990.
120. Kakkanas A and SPANDIDOS DA: Ras p21 onco-protein in the sera of mice carrying an experimentally induced tumor and in human cancer patients. In Vivo 4: 115-120, 1990.
121. Kittas C, Korkolopoulou P, Pangalis GA Tsenga A, Boussiotis VA and SPANDIDOS DA: Expression of c-myc p62 protein in non-Hodgkin's lymphomas. Leukemia and Lymphoma 1: 241-247, 1990.
122. Anderson MLM and SPANDIDOS DA: Onco-suppressor genes. In: Molecular Biology of Cancer Genes. M Sluyser (Ed). Ellis Horwood, pp62-81, 1990.
123. Agnantis NJ and SPANDIDOS DA: Ras and c-myc oncoprotein expression in human colorectal tumors. In: Hereditary colorectal Cancer. J Utsunomiya and HT Lynch (Eds). Springer-Verlag, pp483-487, 1990.
124. SPANDIDOS DA and Anderson MLM: A role of ras oncogenes in carcinoncogenesis and differentiation. In: Molecular Aspects of Development and Aging of the Nervous System. JM Lauder, A Privat, E Giacobini, PS Timiras and A Vernadakis (Eds). Plenum Publ Co, Advances in Experimental Medicine and Biology 265: 127-131, 1990.
125. Nastruzzi C, Barbieri R, Ferroni R, Guarneri M, SPANDIDOS DA and Gambari R: Tetra-amidines exhibiting anti-proteinase activity: effects on oriented migration and in vitro invasiveness of a chinese hamster cell line transfected with the activated human T24 Ha-ras-1 oncogene. Cancer Letters 50: 93-102, 1990.
126. SPANDIDOS DA, Zakinthinos S, Petraki C, Sotsiou F, Yiagnisis M, Dimopoulos AM, Roussos C and Field JK: Expression of ras p21 and myc p62 oncoproteins in small cell and non small cell carcinoma of the lung. Anticancer Research 10: 1105-1114, 1990.
127. SPANDIDOS DA, Zoumpourlis V, Kotsinas A, Tsiriyotis C and Sekeris CE: Response of human immunodeficiency virus long terminal repeat to growth factors and hormones. Anticancer Research 10: 1241-1246, 1990.
128. Karayiannis M, Yiagnisis M, Papadimitriou K, Field JK and SPANDIDOS DA: Evaluation of the ras and myc oncoprotein in benign gastric lesions. Anticancer Research 10: 1127-1134, 1990.
129. SPANDIDOS DA, Zoumpourlis V, Kotsinas A, Maurer HR and Patsilinakos P: Transcriptional activation of the human immunodeficiency virus long terminal repeat sequences by cis-platin. Genetic Analysis Techniques and Applications 7: 138-141, 1990.
130. Zoumpourlis V, Patsilinacos P, Kotsinas A, Maurer HR, Lenas P and SPANDIDOS DA: Cis-platin stimulates the expression from the human immunodeficiency virus long-terminal repeat sequences in human fibroblasts. AntiCancer Drugs 1: 55-58, 1990.
131. SPANDIDOS DA, Frame M and Wilkie NM: Expression of the normal H-ras1 gene can suppress the transformed and tumorigenic phenotypes induced by mutant ras genes. Anticancer Research 10: 1543-1554, 1990.
132. SPANDIDOS DA, Kaloterakis A, Yiagnisis M, Varatsos A and Field JK: Ras, c-myc and c-erbB-2 oncoprotein expression in non-AIDS Mediterranean Kaposi's sarcoma. Anticancer Research 10: 1619-1626, 1990.
133. Linardopoulos S, Malliri A, Pintzas A, Vassilaros S, Tsikkinis A and SPANDIDOS DA: Elevated expression of AP-1 activity in human breast tumors as compared to normal adjacent tissue. Anticancer Research 10: 1711-1714, 1990.
134. Kerr DJ, Khan MZ, Plumb J, Freshney RI and SPANDIDOS DA: The effect of oncogene transfection on epithelial cell response to cytotoxic drugs. Biochemical Pharmacology. Life Sciences Advances 9: 375-379, 1990.
135. Anderson MLM, SPANDIDOS DA and Coggins JR: Electroporation of lymphoid cells: factors affecting the efficiency of transfection. Journal of Biochemical and Biophycical Methods 22: 207-222, 1991.
136. Agnantis NJ, Apostolikas N, Sficas C, Zolota V and SPANDIDOS DA: Immunohistochemical detection of ras p21 and c-myc p62 in colonic adenomas and carcinomas. Hepato-Gastroenterology 38: 239-242, 1991.
137. Zoumpourlis V, Kerr DJ and SPANDIDOS DA: Doxorubicin stimulates transcription from the human immunodeficiency virus long terminal repeat sequences. Cancer Letters 56: 181-185, 1991.
138. Katsanakis CD, Sekeris CE and SPANDIDOS DA: The human immunodeficiency virus long terminal repeat contains sequences showing partial homology to glucocorticoid responsive elements. Anticancer Research 11: 381-384, 1991.
139. SPANDIDOS DA, Zoumpourlis V and Lang JC: Cis-platin responsive sequences in the human c-myc promoter. Anticancer Research 11: 1339-1342, 1991.
140. Khan MZ, SPANDIDOS DA, Kerr DJ, McNicol AM, Lang JC, DeRidder L and Freshney RI: Oncogene transfection of mink lung cells: effects on growth characteristics in vitro and in vivo. Anticancer Research 11: 1343-1348, 1991.
141. Kerr DJ, Plumb JA, Freshney RI, Khan MZ and SPANDIDOS DA: The effect of H-ras and c-myc oncogene transfection on response of mink lung epithelial cells to growth factors and cytotoxic drugs. Anticancer Research 11: 1349-1352, 1991.
142. Koutselini H, Malliri A, Field JK and SPANDIDOS DA: p53 expression in cytologic specimens from benign and malignant breast lesions. Anticancer Research 11: 1415-1420, 1991.
143. Tosca A, Linardopoulos S, Malliri A, Hatziolou E, Nicolaidou A and SPANDIDOS DA: Implication of the RAS and MYC onco-proteins in the pathogenesis of mycosis fungoides. Anticancer Research 11: 1433-1438, 1991.
144. SPANDIDOS DA, Malliri A, and Sekeris CE: Onco-suppressor genes. Review of Clinical Pharmacology and Pharmacokinetics 5: 3-11, 1991.
145. Arvanitis D, Malliri A, Antoniou D, Linardopoulos S, Field JK and SPANDIDOS DA: Ras p21 expression in brain tumors: Elevated expression in malignant astrocytomas and glioblastomas multiforme. In Vivo 5: 317-321, 1991.
146. Field JK, SPANDIDOS DA, Malliri A, Gosney JR, Yiagnisis M and Stell PM: Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck. British Journal of Cancer 64: 573-577, 1991.
147. Pintzas A and SPANDIDOS DA: Sp-1 binding sites within the human H-ras promoter: Potential role of the 6 bp insertion sequence in the T24 H-ras1 gene. Anticancer Research 11: 2067-2070, 1991.
148. Eliopoulos A. Kerr DJ and SPANDIDOS DA: The effect of doxorubicin, daunorubicin and 4'-epidoxorubicin on the exogenous c-myc promoter in mouse erythroleykemia cells. Anticancer Research 11: 2153-2158, 1991.
149. Skalkeas GrD, SPANDIDOS DA, Kostakis A, Balafouta-Tseleni S, Choremi E, Iliopoulos D and Haliassos A: K-ras oncogene mutations in neoplasias of Kidney transplanted patients: Preliminary results with a new technique. Anticancer Research 11: 2091-2094, 1991.
150. Chastre E, Empereur S, DiGioia Y, Bex V, VanRoy F, Caillard I, Tome D, SPANDIDOS DA, Emani S and Gespach C: Induction et activation du pouvoir tumoral et des systems effecteurs de la metastase par les oncogenes ras et src. Cahiers d' Oncologie. Special Issue pp39-40, 1991.
151. SPANDIDOS DA: Ras oncogenes in cell transformation and human cancer. In: ŌBiotechnology of cell RegulationÕ. R Verna and Y Nishizuka (Eds). Serono Symposia Series.Advances in Experimental Medicine. Series Eds L Frati and SA Aaronson. Raven Press, New York, USA, pp205-209, 1991.
152. Eliopoulos A, Kerr DJ and SPANDIDOS DA: The effect of cis-platin and carboplatin on c-myc promoter in erythroleukemia cells. AntiCancer Drugs 2: 597-601, 1991.
153. Wishart GC, Plumb JA, SPANDIDOS DA and Kerr DJ: H-ras transfection in mink lung epithelial cells may induce ŌatypicalÕ ŌmultidrugÕ resistance. European Journal of Cancer 27: 673, 1991.
154. SPANDIDOS DA: Suppression of the phenotype of T24 H-ras1 transformed cells. In: The Super-Family of ras Related Genes. DA Spandidos (Ed). Plenum Publishing Co, pp145-150, 1991.
155. Chomel JC, Grandjouan S, SPANDIDOS DA, Tuilliez M, Bognel C, Kintzis A, Kaplan JC and Haliassos A: Search for correlations between K-ras oncogene activation and pathology, in sporadic and familiar colonic adenomas. In: The Super-Family of ras Related Genes. DA Spandidos (Ed). Plenum Publishing Co, pp153-161, 1991.
156. Nastruzzi C, SPANDIDOS D, Feriotto G, Manfredini S, Simoni D and Gambari R: Ha-RAS-1 transfected cells: Induction to differentiation by natural and synthetic retinoids. In: The super-family of ras Related Genes. DA Spandidos (Ed). Plenum Publishing Co, pp173-181, 1991.
157. Symonds RP, Habeshaw T, Paul J, Kerr DJ, Darling A, Burnett RA, Sotsiou F, Linardopoulos S and SPANDIDOS DA: Oncogene expression and cervical cancer. In: The Super-Family of ras Related Genes. DA Spandidos (Ed). Plenum Publishing Co, pp227-283, 1991.
158. Kerr DJ, Plumb JA, Wishart GC, Khan MZ, Freshney RI and SPANDIDOS DA: The effect of H-ras and c-myc oncogene transfection on the responce of lung epithelial cells to growth factors and cytotoxic drugs. In: The Super-Family of ras Related Genes. DA Spandidos (Ed). Plenum Publishing Co, pp285-294, 1991.
159. Pintzas A, Kotsinas A and SPANDIDOS DA: Transcriptional regulation of c-Ha-ras1 gene. In: The Super-Family of ras Related Genes. DA Spandidos (Ed). Plenum Publishing Co, pp311-316, 1991.
160. SPANDIDOS DA, Karayiannis M, Yiagnisis M, Papadimitriou K and Field JK: Immunohistochemical analysis on the expression of the c-myc oncoprotein in human stomach cancers. Digestion 50: 127-134, 1991.
161. SPANDIDOS DA: Oncogene activation: A prognostic indicator in the development of human tumors. In: Continuing Education Program. Lectures of Invited Guests Presented at the 50th Annual Meeting of the Japan Neurosurgical Society and the International Symposium on Neuroscience for Neurosurgeons, pp72-77, 1991.
162. SPANDIDOS DA: Ras oncogene activation in cell transformation and malignancy. Genetics of Hematological Disorders. CS Bartsocas and D Loukopoulos (Eds). Hemisphere Publ Corp, pp137-140, 1992.
163. Kalmanti M, Kalmantis T, Vassilaki M, Yiagnisis M, Galanopoulos A and SPANDIDOS DA: Immunohistochemical analysis of the ras oncoprotein product p21 in the bone marrow of children with acute leukemia. Genetics of Hematological Disorders. CS Bartsocas and D Loukopoulos (Eds). Hemisphere Publ Corp, pp155-161, 1992.
164. Kalmantis T, Vassilaki M, Kalmanti M, Yiagnisis M, Grenzelias D and SPANDIDOS DA: Elevated expression of the ras p21 oncoprotein in myelodysplastic syndromes as determined by immunohistochemical analysis of bone marrow smears. Genetics of Hematological Disorders. CS Bartsocas and D Loukopoulos (Eds). Hemisphere Publ Corp, pp163-170, 1992.
165. SPANDIDOS DA, Karaiossifidi H, Malliri A, Linardopoulos S, Vassilaros S, Tsikkinis A and Field JK: Expression, of ras, Rb1 and p53 proteins in human breast cancer. Anticancer Research 12: 81-90, 1992.
166. Field JK, SPANDIDOS DA and Stell PM: Overexpression of the p53 gene in head and neck cancer-a genetic link with heavy smoking and drinking. Lancet 339: 502-503, 1992
167. Zoumpourlis V, Kerr DJ and SPANDIDOS DA: Carboplatin as opposed to cis-platin does not stimulate the expression of the human immunodeficiency virus long terminal repeat sequences. Biochemical Pharmacology 43: 650-654, 1992.
168. Tsatsanis C, Tsiriyotis C and SPANDIDOS DA: Hexametlylene bisacetamide and cis-platin stimulate the expression from the HIV-1 long terminal repeat sequence in human MCF-7 cells. In Vivo 6: 145-150, 1992.
169. SPANDIDOS DA, Arvanitis D and Field JK: Ras p21 expression in neuroblastomas and gaglio-neuroblastomas: correlation with patients prognosis. International Journal of Oncology 1: 53-58, 1992.
170. Hassan HT, Tsiryiotis C, Maurer HR and SPANDIDOS DA: Recombinant human interleukin-3 opposes the effects of Vitamin A and D on HL-60 human myeloid leukaemia cells. Anticancer Research 12: 821-826, 1992.
171. Field JK, Yiagnisis M, SPANDIDOS DA, Gosney JR, Papadimitriou K, Vaughan ED and Stell PM: Low levels of ras p21 oncogene expression correlates with clinical outcome in head and neck squamous cell carcinoma. European Journal of Surgical Oncology 18: 168-176, 1992.
172. Field JK, SPANDIDOS DA, Yiagnisis M, Gosney JR, Papadimitriou K and Stell PM: c-erbB-2 expression in squamous cell carcinoma of the head and neck. Anticancer Research 12: 613-620, 1992.
173. Maurer HR, Hassan HT, Tsiriyotis C and SPANDIDOS DA: Recombiant human interferons alpha, beta and gamma reduce the anti-proliferative action of cytarabine in K562 human myeloid leukaemia clonogenic cells. Journal of Cancer Research and Clinical Oncology 118: 329-333, 1992.
174. Haliassos A, Arvanitis D, Parliaras J and SPANDIDOS DA: Detection of hepatitis B virus DNA at high frequency in liver neoplasias using a PCR technique. International Journal of Oncology 1: 125-128, 1992.
175. Russel J, Khan MZ, Kerr DJ and SPANDIDOS DA: The effect of transfection with the oncogenes H-ras and c-myc on the radio-sensitivity of a mink epithelial cell line. Radiation Research 130: 113-116, 1992.
176. Gorgoulis V, Aninos D, Priftis Ch, Evagelopoulou C, Karameris A, Kanavaros P and SPANDIDOS DA: Expression of epidermal growth factor, transforming growth factor-? and epidermal growth factor receptor in thyroid tumors. In Vivo 6: 291-296, 1992.
177. Gorgoulis V, Aninos D, Mikou P, Kanavaros P, Karameris A, Jordanoglu I, Rasidakis A, Velsemes M, Ozanne B and SPANDIDOS DA: Expression of EGF, TGF-? and EGFR in squamous cell lung carcinomas. Anticancer Research 12: 1183-1188, 1992.
178. Kyriakou D, Karkavitsas N, Eliopoulos G and SPANDIDOS DA: Immunohistochemical analysis of the ras p21 oncoprotein in Hashimoto's thyroiditis. Anticancer Research 12: 1189-1194, 1992.
179. Field JK, Malliri A, Jones A and SPANDIDOS DA: Mutations in the p53 gene at codon 249 are rare in squamous cell carcinoma of the head and neck. International Journal of Oncology 1: 253-256, 1992.
180. Zoumpourlis V and SPANDIDOS DA: Hexamethylene bisacetamide stimulates the expression of human immunodeficiency virus long terminal repeat sequences in rat and human fibroblasts. AntiCancer Drugs 3: 163-167, 1992.
181. Hassan HT, Eliopoulos A, Maurer HR and SPANDIDOS DA: Recombinant human GM-CSF enhances the anti-proliferative activity of vitamin D in MCF-7 human breast cancer clonogenic cells. European Journal of Cancer 28A: 1588-1589, 1992.
182. Symonds RP, Habeshaw T, Paul T, Kerr DZ, Darling A, Burnett RA, Sotsiou F, Linardopoulos S and SPANDIDOS DA: Ras, c-myc and c-jun proto-oncogene expression in advanced carcinoma of cervix. Correlation with prognostic indices and survival. The European Journal of Cancer 28A: 1615-1617, 1992.
183. Agnantis NJ, Mahera H, Maounis N and SPANDIDOS DA: Immunohistochemical study of ras and myc oncoproteins in apocrine lesions with and without papillomatosis. European Journal of Gynecological Oncology 8: 309-315, 1992.
184. Papadakis E, Malliri A, Linardopoulos S, Karaiossifidi H, Field JK and SPANDIDOS DA: Ras and p53 expression in non-small cell lung cancer patients: p53 over-expression correlates with a poor prognosis. International Journal of Oncology 1: 403-413, 1992.
185. Haliassos A, Eliopoulos A and SPANDIDOS DA: Oncogenes and onco-suppressor in human leukemias and lymphomas. European School of Oncology. Postgraduate Athens Leukemia Seminar, GA Pangalis (ed), pp63-75, 1992.
186. Haliassos A, Liloglou T, Likourinas M, Doumas C, Ricci N and SPANDIDOS DA: H-ras oncogene mutations in the urine of patients with bladder tumors: description of a non-invasive method for the detection of neoplasia. International Journal of Oncology 1: 731-734, 1992.
187. SPANDIDOS DA: The role of oncogenes and onco-suppressor genes in human breast cancer. Breast cancer: Biological and Clinical Progress. L Dogliotti, A Sapino and G Bussolatti (Eds). Kluwer Academic Publishers, pp3-10, 1992.
188. Delakas D, Agnantis NJ, Parliaras J, Cranidis A and SPANDIDOS DA: The role of ras p21 oncoprotein in human bladder cancer. In: Oncogenes and Molecular Genetics of Urological Tumours. CA Olsson (Ed). Churchill Livingstone, Edinburgh, pp91-94, 1992.
189. Zoumpourlis V, Eliopoulos A and SPANDIDOS DA: Transcriptional activation of the human immunodeficiency virus long terminal repeat sequences by tumor necrosis factor. Anticancer Research 12: 2065-2068, 1992.
190. Kalmanti M, Kalmantis T, Vassilaki M, Galanopoulos A, Grenzelias D and SPANDIDOS DA: The expression of the RAS p21 oncoprotein in the bone marrow smears of children with acute leukemia. Anticancer Research 12: 2177-2180, 1992.
191. SPANDIDOS DA: Oncogenes and onco-suppressor genes in breast cancer. In: Senology. L Ioannidou-Mouzaka, NJ Agnatnis and I Karydas (Eds). Elsevier Science Publishers B.V., pp425-429, 1992.
192. Tiniakos D, SPANDIDOS DA, Yiagnisis M and Tiniakos G: Expression of ras and c-myc oncoproteins and hepatitis B surface antigen in human liver disease. Hepato-Gastroenterology 40: 37-40, 1993.
193. SPANDIDOS DA, Liloglou T, Arvanitis D and Gourtsoyiannis NC: Ras gene activation in human small intestinal tumors. International Journal of Oncology 2: 513-518, 1993.
194. SPANDIDOS DA and Anderson MLM: Oncogene activation and human cancer. In: Oncogene and transgenics: Correlates of cancer risk assessments. C Zervos (Ed). Plenum Publishers, New York, pp61-66, 1993.
195. Haliassos A and SPANDIDOS DA: K-ras oncogene activation in neoplasias of patients with familial adenomatous polyposis or Kidney transplant. In: Oncogenes and transgenics: Correlates of Cancer risk assessments. C Zervos (Ed). Plenum Publishers, New York, pp127-131, 1993.
196. Haliassos A, Liloglou T, Ergazaki M and SPANDIDOS DA: The polymerase chain reaction in medical applications. Review of Clinical Pharmacology and Pharmacokinetics 7: 7-16, 1993.
197. Zoumpourlis V, Kerr DJ and SPANDIDOS DA: Differential interaction of cis-platin with the HIV-1 LTR in a carcinoma cell line. AntiCancer Drugs 4: 77-83, 1993.
198. Eliopoulos AG and SPANDIDOS DA: Changes in FOS/JUN binding activity on a negative regulatory element of c-myc during differentiation of mouse erythroleukemic cells. International Journal of Oncology 2: 883-888, 1993.
199. Linardopoulos S, Papadakis E, Delakas D, Theodosiou V, Cranidis A and SPANDIDOS DA: Human lung and bladder carcinoma tumors as compared to their adjacent normal tissue have elevated AP-1 activity at the retinoblastoma gene promoter. Anticancer Research 13: 257-262, 1993.
200. SPANDIDOS DA, Liloglou T and Field JK: Prognostic significance of oncogenes and tumour-suppressor genes in human malignancy. Stem Cells 11: 194-198, 1993.
201. Tsiriyotis C, SPANDIDOS DA and Sekeris CE: Binding of mitochondrial and nuclear proteins from mouse and human cells to GRE-like elements of mouse mitochondrial DNA. International Journal of Oncology 2: 947-952, 1993.
202. Korkolopoulou P, Patsouris E, Pangalis G, Tsenga A, Elemenoglou J, Thomas-Tsangli E, SPANDIDOS D and Kittas C: A comparative assessment of proliferating cell nuclear antigen, c-myc p62 and nucleotide organizer region staining in non-Hodgkin's lymphoma: A histochemical and immunohistochemical study of 200 cases. Human Pathology 24: 371-377, 1993.
203. Field JK, Malliri A, Buff SA, Gosney JR, Phillips D, SPANDIDOS DA and Jones A: p53 expression in end stage squamous cell carcinoma of the head and neck: correlates with poor survival. International Journal of Oncology 3: 431-435,1993.
204. Nikolaidou A, Liloglou T, Malliri A, Ergazaki M, Tiniakos G, Tiniakos D and SPANDIDOS DA: Detection of hepatitis B virus DNA and mutations in K-ras and p53 genes in human hepatocellular carcinomas. International Journal of Oncology 3: 593-596, 1993.
205. Gonos ES and SPANDIDOS DA: Oncogenes in cellular immortalisation and differentiation. Anticancer Research 13: 1117-1122, 1993.
206. Zoumpourlis V and SPANDIDOS DA: Mitomycin C stimulates the expression of human immunodeficiency virus long terminal repeat sequences in rat and human fibroblasts. Biochemical Pharmacology 46: 178-181, 1993.
207. Kalmantis T, Kalmanti M, Vassilaki M and SPANDIDOS DA: Analysis of immunohistochemical results of the ras oncogene product p21 in myelodysplastic syndromes. Anticancer Research 13: 1103-1106, 1993.
208. Cranidis A, Delakas D, Agnantis NJ and SPANDIDOS DA: Bestimmung des c-MYC onkogenproduktes beim lasenkarzinom. Z Urologie 2: 48, 1993.
209. Anderson MLM and SPANDIDOS DA: Oncogenes and onco-suppressor genes in lung cancer. Respiratory Medicine 87: 413-420, 1993.
210. Linardopoulos S, Gonos ES and SPANDIDOS DA: Abnormalities of retinoblastoma gene structure in human lung tumors. Cancer Letters 71: 67-74, 1993.
211. Kotsinas A, SPANDIDOS DA, Romanowski P and Wyllie AH: Relative expression of wild type and activated Ki-ras2 oncogene in colorectal carcinomas. International Journal of Oncology 3: 841-845, 1993.
212. Gorgoulis V, Giatromanolaki A, Karameris A, Tsatsanis C, Aninos D, Ozanne B, Veslemes M, Jordanoglou J, Trigidou R, Papastamatiou H and SPANDIDOS DA: Epidermal growth factor receptor expression in squamous cell lung carcinomas: An immunohistochemical and gene analysis in formalin-fixed paraffin-embedded material. Virchows Archives A Pathology Anatomy 423: 295-302, 1993.
213. Field JK, Pavelic ZP, SPANDIDOS DA, Stambrook PJ, Jones AS and Gluckman JL: The role of the p53 tumour suppressor gene in squamous cell carcinoma of the head and neck. Archives of Otoraryngology - Head and Neck Surgery 119: 1118-1122, 1993.
214. SPANDIDOS DA, Eliopoulos A and Zoumpourlis V: Regulation of oncogene and AIDS virus expression by cis-platin compounds. Journal of Chemotherapy 5: 778-779, 1993.
215. Chastre E, Empereur SD, Gioia Y, Mareel MM, Van Roy F, Bex V, Emani S, SPANDIDOS DA and Gespach C: Differential effects of the Ha-ras and polyoma middle T oncogenes on cancer progression and cellular differentiation after gene transfer in immortalized and transformed human and rat intestinal epithelial cells. Gastroenterology 105: 1776-1789, 1993.
216. Ergazaki M, Liloglou T, Koffa M, Kostakis A, Haliassos A and SPANDIDOS DA: Detection of the cytomegalovirus by the polymerase chain reaction DNA amplification in a kidney transpanted patient. In Vivo 7: 531-534, 1993.
217. Tseleni-Balafouta S, Gonos ES and SPANDIDOS DA: Expression of ras p21 in benign and malignant thyroid lesions. Oncology Reports 1: 107-110, 1994.
218. Eliopoulos AG and SPANDIDOS DA: Altered binding of the AP-1 protein on a negative regulatory element of c-myc is correlated with the progression of the malignancy of the lung and may contribute to c-myc expression. Oncology Reports 1: 139-143, 1994.
219. Kolettas E, Gonos ES and SPANDIDOS DA: Overexpression of Ha-ras oncogene transforms rodent fibloblasts with low frequency but not human diploid fibroblasts. International Journal of Oncology 4: 43-47, 1994.
220. Gonos ES and SPANDIDOS DA: The retinoblastoma and p53 onco-suppressor genes and their role in human cancer. Cancer Molecular Biology 1: 27-34, 1994.
221. Koffa M, Malamou-Mitsi V, Agnantis NJ and SPANDIDOS DA: Mutational activation of K-ras oncogene in human breast tumors. International Journal of Oncology 4: 573-576, 1994.
222. Koutselini H, Malliri A, Papadakis E, Gillespie DAF and SPANDIDOS DA: c-jun oncogene expression in non-small cell lung cancer. Oncology Reports 1: 353-356, 1994.
223. Zoumpourlis V, Ergazaki M and SPANDIDOS DA: AP-1 recognizes elements on HIV-1 LTR in human epithelial tumor cell lines. Oncology Reports 1: 397-401, 1994.
224. Zoumpourlis V, Papadakis E, Delakas D, Cranidis A, Segas J, Papadakis H and SPANDIDOS DA: Human lung, bladder and head and neck tumors as compared to adjacent normal tissues have elevated AP-1 activity and recognize sequence elements of HIV-1 LTR. Oncology Reports 1: 403-409, 1994.
225. Field JK, Tsiriyotis C, Zoumpourlis V, Howard P, SPANDIDOS DA and Jones AS: Allele loss on chromosome 3 in squamous cell carcinoma of the head and neck and neck correlates with poor clinical prognostic indicators. International Journal of Oncology 4: 543-549, 1994.
226. Linardopoulos S and SPANDIDOS DA: Regulation of the Rb gene by normal and mutated RAS, TPA and EGF. Oncology Reports 1: 533-536, 1994.
227. SPANDIDOS DA, Kiaris H, Lioudaki E and Manousos O: Activating mutations in the K-ras gene in ulcerative colitis and Chohn's disease. Oncology Reports 1: 547-549, 1994.
228. Eliopoulos AG, Kiaris H, Rees RC, Sivridis E, Parsons MA and SPANDIDOS DA: ras gene mutations are a rare event in human melanomas. Oncology Reports 1: 571-575, 1994.
229. Gorgoulis V, Tsatsanis C, Ozanne B and SPANDIDOS DA: Detection of epidermal growth factor receptor and c-erbB-2 gene amplification in transitional cell bladder carcinoma using the differential PCR technique. International Journal of Oncology 4: 1191-1197, 1994.
230. Field JK, Zoumpourlis V, SPANDIDOS DA and Jones AS: p53 expression and mutations in squamous cell carcinoma of the head and neck: correlates with the patients use of tobacco and alcohol. Cancer Detection and Prevention 18: 197-208, 1994.
231. Ergazaki M, Xinarianos G, Koffa M, Liloglou T and SPANDIDOS DA: Detection of human cytomegalovirus by the polymerase chain reaction in immunosuppressed and immunocompromised patients. Oncology Reports 1: 805-808, 1994.
232. Liloglou T, Giannoudis A, Ergazaki M, Koffa M and SPANDIDOS DA: Detection of Epstein-Barr by the polymerase chain reaction in immunosuppressed and immunocompromised patients. Oncology Reports 1: 809-811, 1994.
233. Ergazaki M, Xinarianos G, Giannoudis A, Koffa M, Liloglou T, Kattamis Ch and SPANDIDOS DA: Detection of human cytomegalovirus and Epstein-Barr virus by the polymerase chain reaction in patients with §-thalassaemia. Oncology Reports 1: 813-816, 1994.
234. Koffa M, Koumantakis E, Ergazaki M, Malamou-Mitsi V and SPANDIDOS DA: Detection of ras gene mutations and HPV in lesions of the human female reproductive tract. International Journal of Oncology 5: 189-195, 1994.
235. Kotsinas A, Kiaris H and SPANDIDOS DA: A method to detect and quantitate the expression of normal versus mutant H-ras transcripts at codon 12. International Journal of Oncology 5: 479-483, 1994.
236. Kiaris H, SPANDIDOS DA, Jones AS and Field JK: Loss of heterozygocity and microsatellite instability of the H-ras gene in cancer of the head and neck. International Journal of Oncology 5: 579-582, 1994.
237. SPANDIDOS DA, Chatzipanagiotou M and Zoumpourlis V: Oncogene and onco-suppressor gene lesions in lung cancer. In: Proceedings of the International Congress for Lung Cancer. G. Antypas (Ed.) Monduzzi Editore S.p.A. Bologna, Italy, pp41-45, 1994.
238. SPANDIDOS DA, Zoumpourlis V, Gorgloulis V and Gourtsoyiannis NC: p53 expression in small intestinal tumors. Oncology Reports 1: 885-889, 1994.
239. Liloglou T, Kotsinas A and SPANDIDOS DA: Inducible H-ras gene expression controlled by an allosterically regulated transactivator. Oncology Reports 1: 889-993, 1994.
240. Porter MJ, Field JK, Leung SF, Lo D, Lee JCK, SPANDIDOS DA and Van Hasselt CA: The detection of the c-myc and ras oncogenes in nasopharyngeal carcinoma by immunohistochemistry. Acta Otolaryngologica 114: 105-109, 1994.
241. SPANDIDOS DA, Xinarianos G, Ergazaki M, Giannoudis A and Tsamparlakis J: The presence of herpesviruses in pterygium. International Journal of Oncology 5: 749-752, 1994.
242. Agnantis NJ, Apostolikas N, Zolota V and SPANDIDOS DA: Immunohistochemical detection of ras p21 oncoprotein in breast cancer imprints. Acta Cytologica 38: 335-340, 1994.
243. SPANDIDOS DA and Field JK: Ras oncogenes as prognostic indicators in the development of human tumors. In: GTPase-Controlled Molecular Machines. D. Corda, H. Hamm and A. Luini (Eds). Ares-Serono Symposia Publications 6: 121-127, 1994.
244. Ergazaki M, Xinarianos G, Giannoudis A, Markomichelakis N, Tsamparlakis J and SPANDIDOS DA: Detection of HSV, CMV and EBV by the polymerase chain reaction (PCR) in patients with inflammatory eye diseases. Oncology Reports 1: 1207-1210, 1994.
245. Liloglou T, Tegos C and SPANDIDOS DA: T24 H-ras gene expression increases the activity of phosphoglycerate kinase, enolase and pyruvate kinase and decreases the activity of adenosine deaminase in fibroblast cells. Oncology Reports 1: 1193-1197, 1994.
246. Kiaris H, Jones AS, SPANDIDOS DA, Vaughan ED and Field JK: Loss of heterozygosity on chromosome 8 in squamous cell carcinomas of the head and neck. International Journal of Oncology 5: 1243-1248, 1994.
247. Kotsinas A, Vageli D, Varakliotou A, Anezinis P, Cranidis A and SPANDIDOS DA: Genomic instability and LOH at two polymorphic sites in the H-ras1 gene. International Journal of Oncology 5: 1249-1253, 1994.
248. SPANDIDOS DA: Oncogenes and onco-suppressor genes as prognostic indicators in breast cancer. Proceedings of the Hellenic Society for Breast Cancer Research First International Congress. News Bulletin p32, 1994.
249. SPANDIDOS DA, Chatzipanagiotou M and Zoumpourlis V: Prognostic significance of oncogenes and onco-suppressor genes in lung cancer. In: Proceedings of Seminar on Lung Cancer. European School of Oncology. pp26-29, 1994.
250. Tsatsanis C, Fulton R, Nishizaki K, Tsujimoto H, Levy L, Terry A, SPANDIDOS DA, Onions D and Neil JC: Genetic determinats of feline leukemia virus-induced lymphoid tumors: Patterns of proviral insertion and gene rearrangements. Journal of Virology 68: 8296-8303, 1994.
251. Kolettas E, Gonos ES and SPANDIDOS DA: Retroviral genes - myc. In: Cell and Tissue Culture: Laboratory Procedures. JB Griffiths, A Doyle and DG Newell (Eds). John Wiley and Sons Ltd, UK. 26H: 1.1-1.14, 1994.
252. Gonos ES, Kolettas E and SPANDIDOS DA: Retroviral genes - ras. In: Cell and Tissue Culture: Laboratory Procedures. JB Griffiths, A Doyle and DG Newell (Eds). John Wiley and Sons Ltd, UK. 26H: 2.1-2.11, 1994.
253. SPANDIDOS DA and Koffa M: Activation of ras oncogenes in breast cancer. In: Proceedings of the 2nd European Congress on Senology. E. Kubista, A. Staffen and C. Zielinski (Eds) Monduzzi Editore S.p.A. Bologna, Italy, pp91-97, 1994.
254. Zachos G, Zoumpourlis V, Sekeris CE and SPANDIDOS DA: Binding of the glucocorticoid and estrogen receptors to the human H-ras oncogene sequences. International Journal of Oncology 6: 595-600, 1995.
255. Kiaris H, Eliopoulos AG, Sivridis E, Ergazaki M and SPANDIDOS DA: Activating mutations at ras family genes in prostate cancer. Oncology Reports 2: 427-430, 1995.
256. Giannoudis A, Ergazaki M, Segas J, Giotakis J, Adamopoulos G, Gorgoulis V and SPANDIDOS DA: Detection of Epstein-Barr virus and human papilomavirus in nasopharyngeal carcinoma by the polymerase chain reaction technique. Cancer Letters 89: 177-181, 1995.
257. Kiaris H and SPANDIDOS DA: Analysis of H-ras, K-ras and N-ras genes for expression, mutation and amplification in laryngeal tumours. International Journal of Oncology 7: 75-80, 1995.
258. Field JK, Kiaris H, Howard P, Vaughan ED, SPANDIDOS DA and Jones AS: Microsatellite instability is a frequent event in cancer of the head and neck. British Journal of Cancer 71: 1065-1069, 1995.
259. Karachristos A, Linardopoulos S, Ergazaki M and SPANDIDOS DA: Detection and analysis of hepatitis C virus by a combined RT-PCR method. Variation in the 5' non-coding region of the viral genome. The Journal of Medical Microbiology 42: 367-371, 1995.
260. Kiaris H, SPANDIDOS DA, Jones AS, Vaughan ED and Field JK: Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck. British Journal of Cancer 72: 123-128, 1995.
261. Kiaris H and SPANDIDOS DA: Mutations of ras genes in human tumours. International Journal of Oncology 7: 413-429, 1995.
262. Neville EM, Ellison G, Kiaris H, Stewart M, SPANDIDOS DA, Fox JC and Field JK: Detection of K-ras mutations in non small cell lung carcinoma. International Journal of Oncology 7: 511-514, 1995.
263. Kiaris H, Ergazaki M, Sakkas S, Athanasiadou E and SPANDIDOS DA: Detection of activating mutations in cytological specimens from lung tumours. Oncology Reports 2: 769-772, 1995.
264. Kiaris H, Koumantakis E, Ergazaki M, Sifakis S and SPANDIDOS DA: Instability at microsatellite sequences in spontaneously aborted human embryos provides evidence for a novel mechanism for recurrent miscarriage. Oncology Reports 2: 805-810, 1995.
265. Eliopoulos AG, Maurer HR, Kerr DJ, Hilgard P and SPANDIDOS DA: Cis-platin and two novel platinum compounds increase c-myc transcription in cytotoxic concentrations. Biochemical Pharmacology 50: 33-38, 1995.
266. SPANDIDOS DA, Glarakis IS, Kotsinas A, Ergazaki M and Kiaris H: Ras oncogene activation in benign and malignant colorectal tumors. Tumori. 81 Supplement: 7-11, 1995.
267. Gorgoulis V, Zoumpourlis V, Rassidakis G, Karameris A, Barbatis C, SPANDIDOS DA and Kittas C: Molecular analysis of p53 gene in laryngeal premalignant and malignant lesions. p53 protein immunohistochemical expression is positively related to proliferating cell nuclear antigen (PCNA) labelling index. Virchows Archives A. 426: 339-344, 1995.
268. Koffa M, Simiakaki H, Ergazaki M, Papaefthimiou M, Karakatsani K, Diakomanolis E and SPANDIDOS DA: HPV detection in fixed cytological cervical specimens and correlation with cytology and histology. Oncology Reports 2: 1085-1088, 1995.
269. SPANDIDOS DA, Zoumpourlis V, Zachos G, Toas SH and Halazonetis TD: Specific recognition of a transcriptional element within the human H-ras proto-oncogene by the p53 tumor suppressor. International Journal of Oncology 7: 1029-1034, 1995.
270. Zoumpourlis V, Zachos G, Halazonetis TD and SPANDIDOS DA: Binding of wild-type and mutant forms of p53 protein from human tumors to a specific DNA sequence of the first intron of the H-ras oncogene. International Journal of Oncology 7: 1035-1041, 1995.
271. Kiaris H, Ergazaki M and SPANDIDOS DA: Instability at the H-ras minisatellite is associated with the spontaneous abortion of the embryo. Biochemical and Biophysical Research Communications 214: 788-792, 1995.
272. Biziagos E, Stathopoulos G, Bosch A, Crance J-M, Beher S, Vajiona T, Diez JM, Cajardo R, SPANDIDOS DA, Papaevangelou G, Schwartzbrod L and Deloiance R: Development of an extraction - concentration method for hepatitis A virus recovery from laboratory - contaminated oysters and after the natural accumulation of virus in shellfish. In: Shellfish Depuration. Poggi R and Le Gall J-Y (eds). 1 Fremer, France, pp425-426, 1995.
273. Field JK, Kiaris H, Risk JM, Tsiriyotis C, Adamson R, Zoumpourlis V, Rowley H, Taylor K, Whittaker J, Howard P, Beirne JC, Gosney JR, Woulgar J, Vaughan ED, SPANDIDOS DA and Jones AS: Head and neck cancer allelotype indicates an ordered allele loss consistent with a two hit model of carcinogenesis. British Journal of Cancer 72: 1180-1188, 1995.
274. Koffa M, Koumantakis E, Ergazaki M, Tsatsanis C and SPANDIDOS DA: Association of herpesvirus infection with the development of genital cancer. International Journal of Cancer 63: 58-62, 1995.
275. SPANDIDOS DA and Kiaris H: Gene therapy. In: Therapeutic Controversies in Oncology. Throuvalas N and Scalliet P (eds). European School of Oncology, pp308-312, 1995.
276. Gorgoulis V, Sfikakis PP, Karameris A, Papastamatiou H, Trigidou R, Veslemes M, SPANDIDOS DA, Sfikakis P and Jordanoglou J: Molecular and immunohistochemical study of class I growth factor receptors in squamous cell lung carcinomas. Pathology Research and Practice 191: 973-981, 1995.
277. Kiaris H, Spanakis N, Ergazaki M, Sourvinos G and SPANDIDOS DA: Loss of heterozygosity at 9p and 17q (BRCA1) in laryngeal tumours. Cancer Letters 97: 129-134, 1995.
278. Archer SG, Eliopoulos A, SPANDIDOS DA, Barnes D, Ellis I, Blamey R, Nicholson R and Robertson J: Expression of ras-p21, p53 and c-erb-B2 in advanced breast cancer and response to first line hormonal therapy. British Journal of Cancer 72: 1259-1266, 1995.
279. Kiaris H, Ergazaki M, Segas J and SPANDIDOS DA: Detection of Epstein-Barr virus genome in squamous cell carcinoma of the larynx. The International Journal of Biological Markers 10: 211-215, 1995.
280. Kiaris H, Koumantakis E, Ergazaki M and SPANDIDOS DA: Microsatellite instability in aborted embryos. Molecular Human Reproduction 2: 72-74, 1996.
281. Field JK and SPANDIDOS DA: Oncogenes and tumor suppressor genes as prognostic indicators in the development of human tissues. In: Regulation of Proliferation of Neoplastic Cells. L Pusztai, CE Lewis and E Yap (Eds). Oxford University Press. pp82-104, 1996.
282. Kiaris H, Ergazaki M, Nikolaou I, Papadimitriou K and SPANDIDOS DA: Detection of herpes virus-like DNA sequence in Mediterranian Kaposi's sarcoma. Oncology Reports 3: 355-356, 1996.
283. SPANDIDOS DA, Ergazaki M, Arvanitis D and Kiaris H: Microsatellite instability in human atherosclerotic plaques. Biochemical and Biophysical Research Communications 220: 137-140, 1996.
284. SPANDIDOS DA, Ergazaki M, Hatzistamou J, Kiaris H, Bouros D, Tzortzaki EG and Siafakas NM: Microsatellite instability in patients with chronic obstructive pulmonary disease. Oncology Reports 3: 489-491, 1996.
285. Noutsou A, Koffa M, Ergazaki M, Siafakas N and SPANDIDOS DA: Detection of human papilloma virus (HPV) and K-ras mutations in human lung carcinomas. International Journal of Oncology 8: 1089-1093, 1996.
286. SPANDIDOS DA and Kiaris H: Molecular biology, growth factors and oncogenesis in bladder carcinoma. Proceedings of the European School of Oncology Postgraduate Course on Urological Cancer pp21-22, 1996.
287. SPANDIDOS DA, Kiaris H, Sourvinos G, Zachos G and Ergazaki M: The role of ras oncogenes and p53 onco-suppressor gene in human cancer. In: Proceedings of the Balkan Congress of Oncology, G. Antypas (ed). Monduzzi Editore S.P.A Bologna (Italy) pp533-538, 1966.
288. SPANDIDOS DA, Koffa M, Sourvinos G and Kiaris H: Oncogenes and onco-suppressor genes in the prevention and therapy of breast cancer. In: Breast Cancer, Advances in Biology and Therapeutics. F. Calvo, M. Crepin, H. Magdelenat (eds). John Libbey Eurotext pp27-31, 1996.
289. Gonos ES and SPANDIDOS DA: The role of cdc2, cdc25 and cyclin A genes in the maintenance of immortalization and growth arrest in a rat embryonic fibroblast conditional cell line. Cell Biology International 20: 159-167, 1996.
290. Kiaris H and SPANDIDOS DA: Quantitation of the allelic imbalance provides evidence on tumour heterogeneity: A hypothesis. Mutation Research 354: 35-39, 1996.
291. Kiaris H, Hatzistamou J and SPANDIDOS DA: Instabillity at the H-ras minisatellite in human atherosclerotic plaques. Atherosclerosis 125: 47-51, 1996.
292. Hatzistamou J, Kiaris H, Ergazaki M and SPANDIDOS DA: Loss of heterozygosity and microsatellite instability in human atherosclerotic plaques. Biochemical Biophysical Research Communications 225: 186-190, 1996.
293. Zachos G, Varras M, Koffa M, Ergazaki M and SPANDIDOS DA: Glucocorticoid and estrogen receptors have elevated activity in human endometrial and ovarian tumors as compared to the adjacent normal tissues and recognize sequence elements of the H-ras proto-oncogene. Japanese Journal of Cancer Research 87: 916-922, 1996.
294. Cranidis A, Delakas D, Anezinis P, Agnantis N, Haliassos A and SPANDIDOS DA: Expression of the ras and myc oncogenes in bladder tumors and its correlation with staging and grading of the tumours. Acta Urologica Italica 10: 237-242, 1996.
295. Christeli E, Zoumpourlis V, Kiaris H, Ergazaki M, Vassilaros S and SPANDIDOS DA: TGF-§1 overexpression in breast cancer: correlation with clinicopathological data. Oncology Reports 3: 1115-1118, 1996.
296. Zoumpourlis V, Ergazaki M and SPANDIDOS DA: Transcriptional activation of the human immunodeficiency virus long terminal repeat sequences by retinoic acid in human epithelial and fibroblast tumor cell lines. The International Journal of Biological Markers 11: 153-158, 1996.
297. Gorgoulis VG, Zoumpourlis V, Rassidakis GZ, Karameris A, Rassidakis AN, SPANDIDOS DA and Kittas C: A molecular and immunohistochemical study of the MDM2 protein isoforms and p53 gene product in bronchogenic carcinoma. Journal of Pathology 180: 129-137, 1996.
298. Varras MN, Koffa M, Koumantakis E, Ergazaki M, Protopapa E, Miehalas St and SPANDIDOS DA: ras gene mutations in human endometrial carcinoma. Oncology 53: 505-510, 1996.
299. Vageli D, Kiaris H, Delakas D, Anezinis P, Cranidis A and SPANDIDOS DA: Transcriptional activation of H-ras, K-ras and N-ras proto-oncogenes in human bladder tumors. Cancer Letters 107: 241-247, 1996.
300. Gougopoulou DM, Kiaris H, Ergazaki M, Anagnostopoulos NI, Grigoraki V and SPANDIDOS DA: Mutations and expression of the ras family genes in leukemias. Stem Cells 14: 725-729, 1996.
301. Rowley H, Jones A, SPANDIDOS DA and Field J: Definition of a tumor suppressor gene locus on the short arm of chromosome 3 in squamous cell carcinoma of the head and neck by means of microsatellite markers. Archives of Otolaryngology Head and Neck Surgery 122: 497-501, 1996.
302. Demonacos CV, Karayani N, Hatzoglou E, Tsiriyiotis C, SPANDIDOS DA and Sekeris CE: Mitochondrial genes as sites of primary action of steroid hormones. Steroids 61: 226-232, 1996.
303. Zachos G, Varras M, Koffa M, Ergazaki M and SPANDIDOS DA: The association of the H-ras oncogene and steroid hormone receptors in gynecological cancer. The Journal of Experimental Therapeutics and Oncology 1: 335-341, 1996.
304. SPANDIDOS DA, Sourvinos G and Koffa M: ras genes, p53 and HPV as prognostic indicators in human cancer (Review). Oncology Reports 4: 211-218, 1997.
305. Liloglou T, Ross H, Prime W, Donnelly RJ, SPANDIDOS DA, Gosney JR and Field JK: p53 gene aberrations in non-small-cell lung carcinomas from a smoking population. British Journal of Cancer 75: 1119-1124, 1997.
306. Koffa M, Kalmanti M, Sakalidou A, Kanavaros P, Liloglou T and SPANDIDOS DA: N-ras and K-ras genes point mutations in childhood lymphomas. Archive of Oncology 5: 5-7, 1997.
307. Constantinidou M, Chalevelakis G, Economopoulos T, Koffa M, Liloglou T, Anastassiou C, Yalouris A, SPANDIDOS DA and Raptis S: Codon 12 ras mutations in patients with myelodysplastic syndrome: incidence and prognostic value. Annals of Hematology 74: 11-14, 1997.
308. Sourvinos G, Kiaris H, Tsikkinis A, Vassilaros S and SPANDIDOS DA: Microsatellite instability and loss of heterozygosity in primary breast tumors. Tumor Biology 18: 157-166, 1997.
309. Tsopanomichalou M, Ergazaki M and SPANDIDOS DA: Evaluation of Western blot in routine diagnosis of hepatitis C virus. International Journal of Biological Markers 12: 35-41, 1997.
310. Parissis J, Arvanitis DL, Sourvinos G and SPANDIDOS DA: A primary cardiac leiomyosarcoma with mutation at H-ras codon 12. Oncology Reports 4: 807-808, 1997.
311. SPANDIDOS DA, Sourvinos G, Kiaris H and Tsamparlakis J: Microsatellite instability and loss of heterozygosity in human pterygium. British Journal of Ophthalmology 81: 493-496, 1997.
312. Varras M, Zachos G and SPANDIDOS DA: Endometrial carcinoma in a breast cancer patient treated with tamoxifen: activation of K-ras proto-oncogene. Oncology Reports 4: 1045-1046, 1997.
313. Koffa M and SPANDIDOS DA: Oncogenes and onco-suppressor genesin female genital cancer. In: Adolescent Gynecology and Endocrinology: Basic and Clinical Aspects. G. Creatsas, G. Mastorakos and G.P. Chrousos (eds). Annals of the New York Academy of Sciences, 816: 347-355, 1997.
314. Tsiriyotis C, SPANDIDOS DA and Sekeris CE: The mitochondrion as a primary site of action of glucocorticoids: Mitochondrial nucleotide sequences showing similarity to hormone response elements confer dexamethasone inducibility to chimaeric genes transfected in LATK-cells. Biochemical Biophysical Research Communications 235: 349-354, 1997.
315. Tsopanomichalou M, Ergazaki M, Linardopoulos S and SPANDIDOS DA: Detection of hepatitis C virus in sera and genotyping according to the 5' non-coding region. Oncology Reports 4: 1171-1174, 1997.
316. Kolettas E, SPANDIDOS DA and Rosenberger RF: SV40 transformation of embryonic human diploid fibroblasts results in multiple molecular changes. International Journal of Oncology 11: 717-725, 1997.
317. Liloglou T, Scholes AGM, SPANDIDOS DA, Vaughan ED, Jones AS and Field JK: p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability. Cancer Research 57: 4070-4074, 1997.
318. Zachos G and SPANDIDOS DA: Expression of ras proto-oncogenes: regulation and implications in the development of human tumors. Critical Reviews in Oncology/Hematology 26: 65-75, 1997.
319. Sifakis S, Koumantakis E, Koffa M, Ergazaki M and SPANDIDOS DA: Detection of herpes simplex virus (HSV) in aborted material using the polymerase chain reaction technique. Gynecologic and Obstetric Investigation 45: 109-115, 1998.
320. Sifakis S, Ergazaki M, Sourvinos G, Koffa M, Koumantakis E and SPANDIDOS DA: Evaluation of Parvo B19, CMV and HPV viruses in human aborted material using the polymerase chain reaction technique. European Journal of Obstetrics and Gynecology and Reproductive Biology 76: 169-173, 1998.
321. Zachos G and SPANDIDOS DA: Transcriptional regulation of the H-ras1 proto-oncogene by DNA binding proteins: mechanisms and implications in human tumorigenesis. Gene Therapy and Molecular Biology 1: 629-639, 1998.
322. Froudarakis ME, Sourvinos G, Fournel P, Court-Fortune I, Bouros D, Vergnon J-M, SPANDIDOS DA and Siafakas NM: Microsatellite instability and loss of heterozygocity at chromosomes 9 and 17 in non-small-cell lung cancer. Chest 113: 1091-1094, 1998.
323. Diakoumis E, Sourvinos G, Kiaris H, Delakas D, Cranidis A and SPANDIDOS DA: Genetic instability in renal cell carcinomas. European Urology 33: 227-232, 1998.
324. Sourvinos G and SPANDIDOS DA: Decreased BRCA1 expression levels may arrest the cell cycle through activation of p53 checkpoint in human sporadic breast tumours. Biochemical and Biophysical Research Communications 245: 75-80, 1998.
325. Zachos G and SPANDIDOS DA: Transcriptional regulation of the c-H-ras1 gene by the P53 protein is implicated in the development of human endometrial and ovarian tumours. Oncogene 16: 3013-3019, 1998.
326. Dokianakis DN, Sourvinos G, Sakkas S, Athanasiadou E and SPANDIDOS DA: Detection of HPV and ras gene mutations in cervical smears from female genital lesions. Oncology Reports 5: 1195-1198, 1998.
327. Detorakis E, Miyakis S and SPANDIDOS DA: Molecular genetics of malignant melanoma. Proceedings European School of Oncology. Melanoma - Soft Tissue Sarcomas, pp21-26, 1998.
328. Glarakis IS, Savva S and SPANDIDOS DA: Activation of the ras genes in malignant and premalignant colorectal tumors. Oncology Reports 5: 1451-1454, 1998.
329. Miyakis S, Sourvinos G and SPANDIDOS DA: Differential expression and mutation of the ras family genes in human breast cancer. Biochemical Biophysical Research Communications 251: 609-612, 1998.
330. Detorakis ET, Sourvinos G, Tsamparlakis J and SPANDIDOS DA: Evaluation of loss of heterozygosity and microsatellite instability in human pterygium: Clinical correlations. British Journal of Ophthalmology 82: 1324-1328, 1998.
331. Rizos E, Sourvinos G and SPANDIDOS DA: Loss of heterozygocity at 8p, 9p and 17q in laryngeal cytological specimens. Oral Oncology 34: 519-523, 1998.
332. Detorakis ET and SPANDIDOS DA: p16 alterations in metastatic melanoma (Editorial). Journal of BUON 4: 269-270, 1998.
333. SPANDIDOS DA, Koumantakis E, Sifakis S and Sourvinos G: Microsatellite mutations in spontaneously aborted embryos. Fertility and Sterility 70: 892-895, 1998.
334. Zachos G, Koumantakis E, Vareltzidis A and SPANDIDOS DA: Evidence for loss of heterozygocity in human psoriatic lesions. British Journal of Dermatology 139: 974-977, 1998.
335. Varras MN, Sourvinos G, Diakomanolis E, Koumantakis E, Flouris GA, Lekka-Katsouli J, Michalas S and SPANDIDOS DA: Detection and clinical correlations of ras gene mutations in human ovarian tumors. Oncology 56: 89-96, 1999.
336. Sourvinos G, Parissis J, Sotsiou F, Arvanitis DL and SPANDIDOS DA: Detection of microsatellite instability in sporadic cardiac myxomas. Cardiovascular Research 42: 728-732, 1999.
337. Kozobolis VP, Detorakis ET, Sourvinos G, Pallikaris IG and SPANDIDOS DA: Loss of heterozygosity in pseudoexfoliation syndrome. Investigative Opthalmology and Visual Science 40: 1255-1260, 1999.
338. Sourvinos G, Tsatsanis C and SPANDIDOS DA: Overexpression of the Tpl-2/Cot oncogene in human breast cancer. Oncogene 18: 4968-4973, 1999.
339. Tsopanomichalou M, Kouroumalis E, Ergazaki M and SPANDIDOS DA: Loss of heterozygosity and microsatellite instability in human hepatic lesions. Liver 19: 305-311, 1999.
340. Siafakas NM, Tzortzaki EG, Sourvinos G, Bouros D, Tzanakis N, Kafatos A and SPANDIDOS DA: Microsatellite DNA instability in COPD. Chest 116: 47-51, 1999.
341. Dokianakis DN, Papaefthimiou M, Tsiveleka A and SPANDIDOS DA: High prevalence of HPV 18 in correlation with ras gene mutations and clinicopathological parameters in gynecological malignancies studied from stained cytological smears. Oncology Reports 6: 1327-1331, 1999.
342. Rizos E, Sourvinos G, Arvanitis DA, Velegrakis G and SPANDIDOS DA: Low incidence of H-, K- and N-ras oncogene mutations in cytological specimens of laryngeal tumors. Oral Oncology 35: 561-563, 1999.
343. Dokianakis DN, Varras MN, Papaefthimiou M, Apostolopoulou J, Simiakaki H, Diakomanolis E and SPANDIDOS DA: ras gene activation in malignant cells of human ovarian carcinoma peritoneal fluids. Clinical and Experimental Metastasis 17: 293-297, 1999.
344. Vassilakis DA, Sourvinos G, Psathakis K, Markatos M, SPANDIDOS DA, Siafakas NM and Bouros D: Microsatellite instability and loss of heterozygocity in pulmonary sarcoidosis. American Journal of Respiratory and Critical Care Medicine 160: 1729-1733, 1999.
345. SPANDIDOS DA, Sourvinos G and Miyakis S: Transcriptional activation of the ras oncogenes and implications of BRCA1 in the cell cycle regulation through p53 checkpoint. Gene Therapy and Molecular Biology 3: 373-378, 1999.
346. Karachristos A, Liloglou T, Field JK, Deligiorgi E, Kouskouni E and SPANDIDOS DA: Microsatellite instability and p53 mutations in hepatocellular carcinoma. Molecular Cell Biology Research Communications 2: 155-161, 1999.
347. Dokianakis DN, Koumantaki E, Billiri K and SPANDIDOS DA: P53 codon 72 polymorphism as a risk factor in the development of HPV-associated non-melanoma skin cancers in immunocompetent hosts. International Journal of Molecular Medicine 5: 405-409, 2000.
348. Katsama A, Sourvinos G, Zachos G and SPANDIDOS DA: Allelic loss at the BRCA1, BRCA2 and TP53 loci in human sporadic breast carcinoma. Cancer Letters 150: 165-170, 2000.
349. SPANDIDOS DA, Dokianakis DN, Kallergi G and Angelakis E: Molecular basis of gynecological cancer. Annals of the New York Academy of Sciences 900: 56-64, 2000.
350. Tsatsanis C and SPANDIDOS DA: The role of oncogenic kinases in human cancer. International Journal of Molecular Medicine 5: 583-590, 2000.
351. Dokianakis DN and SPANDIDOS DA: P53 codon 72 polymorphism as a risk factor in the development of HPV-associated cervical cancer. Molecular Cell Biology Research Communications 3: 111-114, 2000.
352. Detorakis ET, Drakonaki EE and SPANDIDOS DA: Molecular genetic alterations and viral presence in ophthalmic pterygium. International Journal of Molecular Medicine 6: 35-41, 2000.
353. SPANDIDOS DA and Sourvinos G: Molecular biology of bladder cancer. Proceedings of the European School of Oncology Postgraduate Course on Urological Cancer, pp188-191, 2000.
354. Saridaki Z, Koumantaki E, Papadopoulos O, Zoras O and SPANDIDOS DA: High frequency of loss of heterozygosity on chromosome region 9p21-p22 but lack of p16INK4a/p19ARF mutations in Greek patients with cell carcinoma of the skin. The Journal of Investigative Dermatology 115: 719-725, 2000.
355. Vassilakis DA, Sourvinos G, SPANDIDOS D, Siafakas NM and Bouros D: Frequent genetic alterations at the microsatellite level in cytologic sputum samples of patients with idiopathic pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine 162: 1115-1119, 2000.
356. Gaki V, Tsopanomichalou M, Sourvinos G, Tsiftsis D and SPANDIDOS DA: Allelic loss in chromosomal region 1q21-23 in breast cancer is associated with peritumoural angiolymphatic invasion and extensive intraductal component. European Journal of Surgical Oncology 26: 455-460, 2000.
357. Miyakis S, Sourvinos G, Liloglou TL, Stathopoulos GP, Field JK and SPANDIDOS DA: The Von Hippel-Lindau (VHL) tumor suppressor gene is not mutated in sporadic human colon adenocarcinomas. International Journal of Cancer 88: 503-505, 2000.
358. Winter AG, Sourvinos G, Allison SJ, Tosh K, Scott PH, SPANDIDOS DA and White RJ: RNA polymerase III transcription factor TFIIIC2 is overexpressed in ovarian tumours. Proceedings of the National Academy of Sciences USA 97: 12619-12624, 2000.
359. Papadakis EN, Dokianakis DN and SPANDIDOS DA: P53 codon 72 polymorphism as a risk factor in the development of breast cancer. Molecular Cell Biology Research Communications 3: 389-392, 2000.
360. Sourvinos G, Tsatsanis C and SPANDIDOS DA: Mechanisms of retrovirus-induced oncogenesis. Folia Biologica 46: 226-232, 2000.
361. Goumenou AG, Arvanitis DA, Matalliotakis IM, Koumantakis EE and SPANDIDOS DA: Loss of heterozygocity in adenomyosis on hMSH2, hMLH1, p16ink4 and GALT loci. International Journal of Molecular Medicine 6: 667-671, 2000.
362. Biliris KA, Koumantakis E, Dokianakis DN, Sourvinos G and SPANDIDOS DA: Human papillomavirus infection of non melanoma skin cancers in immunocompetents hosts. Cancer Letters 161: 83-88, 2000.
363. SPANDIDOS DA, Flouris GA, Kalantzi MV, Parissis JT and Arvanitis DA: Genetic basis of atherosclerosis. Proceedings of the 2nd International Meeting of the Onassis Cardiac Surgery Center. P. Alivizatos, H. Boudoulas, L.H. Edmunds Jr and G.M. Palatianos (Eds), pp168-172, 2000.
364. Flouris GA, Arvanitis DA, Parissis JT, Arvanitis DL and SPANDIDOS DA: Loss of heterozygocity in DNA mismatch repair genes in human atherosclerotic plaques. Molecular Cell Biology Research Communications 4: 62-65, 2000.
365. Tsatsanis ChA and SPANDIDOS DA: Signal transduction pathways in cancer cells: novel targets for therapeutic intervention. Gene Therapy and Molecular Biology 5: 111-119, 2000.
366. SPANDIDOS DA: Editorial. Clarity is the key to success. International Journal of Molecular Medicine 7: 579, 2001.
367. Sourvinos G, Kazanis I, Delakas D, Cranidis A and SPANDIDOS DA: Genetic detection of bladder cancer by microsatellite analysis of p16, RB1 and p53 tumor suppressor genes. The Journal of Urology 165: 249-252, 2001.
368. Zafiropoulos A, Baritaki S, Sioumpara M, SPANDIDOS DA and Krambovitis E: V3 induces in human normal cell populations an accelerated macrophage-mediated proliferation - apoptosis phenomenon of effector T cells when they respond to their cognate antigen. Biochemical Biophysical Research Communications 281: 63-70, 2001.
369. Goumenou AG, Arvanitis DA, Matalliotakis IM, Koumantakis EE and SPANDIDOS DA: Microsatellite DNA assays in endometriosis reveal allelic imbalance in p16ink4, GALT, p53 and APOA2 loci. Fertility and Sterility 75: 160-165, 2001.
370. Detorakis ET, Sourvinos G and SPANDIDOS DA: Detection of herpes simplex virus and human papilloma virus in ophthalmic pterygium. Cornea 20: 164-167, 2001.
371. Sourvinos G, Miyakis S, Liloglou TL, Field JK and SPANDIDOS DA: The von Hippel-Lindau tumor suppressor gene is not involved in sporadic human breast cancer. Tumor Biology 22: 131-136, 2001.
372. Tsatsanis C and SPANDIDOS DA: From the research lab to diagnosis, prognosis and treatment; the K-ras paradigm. Editorial Journal of B.U.O.N. 6: 5-6, 2001.
373. Markaki EA, Tsopanomichalou M, Dimitriou H, Stiakaki E, Perdikoyanni Ch, SPANDIDOS D and Kalmanti M: Mutations of retinoblastoma gene (Rb-1) as a prognostic factor in children with acute leukemia and neuroblastoma. Pediatric Hematology and Oncology 18: 1-10, 2001.
374. Dialyna IA, Arvanitis DA and SPANDIDOS DA: Genetic polymorphisms and transcriptional pattern of CYP1A1, AhR, GSTM1, GSTP1 and GSTT1 genes in breast cancer. International Journal of Molecular Medicine 8: 79-87, 2001.
375. Zafiropoulos A, Baritaki S, SPANDIDOS DA and Krambovitis E: Disregulation of effector CD4+ T cell function by the V3 domain of the HIV-1 gp120 during antigen presentation. Biochemical Biophysical Research Communication 284: 875-879, 2001.
376. Skliros EA, Lionis C, Sotiropoulos A, Foudoulaki L, Kouroumalis E and SPANDIDOS DA: Hepatitis B and C markers in a Kurdish refugees camp in Greece. Journal of Gastroenterology and Hepatology 16: 839-840, 2001.
377. Sourvinos G, Rizos E and SPANDIDOS DA: p53 codon 72 polymorphism is linked to the development and not progression of benign and malignant laryngeal tumours. Oral Oncology 37: 572-578, 2001.
378. Vassilakis DA, Sourvinos G, Pantelidis P, SPANDIDOS DA, Siafakas NM and Bouros D: Extended genetic alterations in a patient with pulmonary sarcoidosis, a benign disease. Sarcoidosis Vasculitis and Diffuse Lung Diseases 18: 307-310, 2001.
379. Miniati P, Sourvinos G, Michalodimitrakis M and SPANDIDOS DA: Loss of heterozygocity on chromosomes 1, 2, 8, 9 and 17 in cerebral atherosclerotic plaques. International Journal of Biological Markers 16: 167-171, 2001.
380. Arvanitis DA, Goumenou AG, Matalliotakis IM, Koumantakis EE and SPANDIDOS DA: Low-penetrance genes are associated with increased susceptibility to endometriosis. Fertility and Sterility 76: 1202-1206, 2001.
381. Koulentaki ME, Ergazaki M, Moschandrea J, Spanoudakis S, Tzagarakis N, Drandakis PE, SPANDIDOS DA and Kouroumalis EA: Prevalence of hepatitis B and C markers in high-risk hospitalised patients in Crete: a five-year observational study. BioMed Central Public Health 1: 17, 2001 (http://www.biomedcentral.com/1471-2458/1/17).
382. Stefanaki IM, Tosca AD, Themelis GC, Vazgiouraki EM, Dokianakis DN, Panayotidis JG, SPANDIDOS DA and Balas CJ: In vivo detection of human papilloma virus-induced lesions of anogenital area after application of acetic acid: A novel and accurate approach to a trivial method. Journal of Photochemistry and Photobiology B: Biology 65: 115-121, 2001.
383. Prokopakis P, Sourvinos G, Koumantaki Y, Koumantakis E and SPANDIDOS DA: K-ras mutations and HPV infection in cervicitis and intraepithelial neoplasias of the cervix. Oncology Reports 9: 129-133, 2002.
384. Manolaraki M, Arvanitis DA, Sourvinos G, Sifakis S, Koumantakis E and SPANDIDOS DA: Frequent loss of heterozygocity in chromosomal region qpter-p13 in tumor biopsies and cytological material of uterine cervical cancer. Cancer Letters 176: 175-181, 2002.
385. Zetterberg H, Regland B, Palmer M, Ricksten A, Palmqvist L, Rymo L, Arvanitis DA, SPANDIDOS DA and Blennow K: Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos. European Journal of Human Genetics 10: 113-118, 2002.
386. Soulitzis N, Sourvinos G, Dokianakis DN and SPANDIDOS DA: p53 codon 72 polymorphism and its association with bladder cancer. Cancer Letters 179: 175-183, 2002.
387. Zetterberg H, Palmer M, Ricksten A, Poirier J, Palmqvist L, Rymo L, Zafiropoulos A, Arvanitis DA, SPANDIDOS DA and Blennow K: Influence of the apolipoprotein E e4 allele on human embryonic development. Neuroscience Letters 324: 189-192, 2002.
388. Arvanitis DA, Angelakis E, Koumantakis EE and SPANDIDOS DA: Allelic imbalance in hMLH1 or BRCA2 loci associated with response of cervical and endometrial cancer to radiotherapy. International Journal of Molecular Medicine 10: 55-63, 2002.
389. Demopoulos K, Arvanitis DA, Vassilakis DA, Siafakas NM and SPANDIDOS DA: MYCL1, FHIT, SPARC, p16INK4 and TP53 genes associated to lung cancer in idiopathic pulmonary fibrosis. Journal of Cellular and Molecular Medicine 6: 215-222, 2002.
390. Arvanitis DA, Goumenou AG, Matalliotakis IM, Koumantakis EE and SPANDIDOS DA: Detecting genetic differences (Letter to the Editor). Fertility and Sterility 78: 442-443, 2002.
391. SPANDIDOS DA, Sourvinos G, Tsatsanis C and Zafiropoulos A: Normal ras genes: Their onco-suppressor and pro-apoptotic functions. International Journal of Oncology 21: 237-241, 2002.
392. Xinarianos G, Liloglou T, Prime W, Sourvinos G, Karachristos A, Maloney P, Gosney GR, SPANDIDOS DA and Field JK: Molecular alterations in the cell cycle regulators p53, Rb and p21 in relation to the expression of the DNA mismatch repair proteins MLH1 and MSH2 in non-small cell lung carcinomas. International Journal of Cancer 101: 248-252, 2002.
393. Zetterberg H, Rymo L, Coppola A, D'Angelo A, SPANDIDOS DA and Blennow K: MTHFR CG77T and A1298C polymorphisms and mutated sequences occurring in CIS. European Journal of Human Genetics 10: 579-582, 2002.
394. Baritaki S, Zafiropoulos A, Sioumpara M, Politis M, SPANDIDOS DA and Krambovitis E: Ionic interaction of the HIV-1 V3 domain with CCR5 and deregulation of T lymphocyte function. Biochemical and Biophysical Research Communications 298: 574-580, 2002.
395. Papadakis ED, Soulitzis N and SPANDIDOS DA: Association of p53 codon 72 polymorphism with advanced lung cancer: The Arg allele is preferentially retained in tumours arising in Arg/pro germline heterozygotes. British Journal of Cancer 87: 1013-1018, 2002.
396. Zetterberg H, Regland B, Palmer M, Rymo L, Zafiropoulos A, Arvanitis DA, SPANDIDOS DA and Blennow K: The transcobalamin II codon 259 polymorphism influences the risk of human spontaneous abortion. Human Reproduction 17: 3033-3036, 2002.
397. Detorakis ET, Kozobolis VP, Pallikaris IG and SPANDIDOS DA: Detection of herpes simplex virus in pseudoexfoliation syndrome and exfoliation glaucoma. Acta Ophthalmologica 80: 612-616, 2002.
398. Miyakis S and SPANDIDOS DA: Allelic loss in breast cancer. Cancer Detection and Prevention 26: 426-434, 2002.
399. Demopoulos K, Arvanitis DA, Vassilakis DA, Siafakas NM and SPANDIDOS DA: Genomic instability on hMSH2, hMLH1, CD48 and IRF4 loci in pulmonary sarcoidosis. International Journal of Biological Markers 17: 224-230, 2002.
400. Saridaki Z, Liloglou T, Zafiropoulos A, Koumantaki E, Zoras O and SPANDIDOS DA: Mutational analysis of CDKN2A genes in patients with squamous cell carcinoma of the skin. British Journal of Dermatology 148: 1-11, 2003.
401. Arvanitis DA, Koumantakis GE, Goumenou AG, Matalliotakis IM, Koumantakis EE and SPANDIDOS DA: CYP1A1, CYP19 and GSTM1 polymorphisms increase the risk of endometriosis. Fertility and Sterility 79: 702-709, 2003.
402. Miyakis S, Liloglou T, Kearney S, Xinarianos G, SPANDIDOS DA and Field JK: Absence of mutations in the VHL gene but frequent loss of heterozygocity at 3p25-26 in non-small cell lung carcinomas. Lung Cancer 39: 273-277, 2003.
403. Arvanitis DA, Papadakis E, Zafiropoulos A and SPANDIDOS DA: Fractional allele loss is a valuable marker for human lung cancer detection in sputum. Lung Cancer 40: 55-66, 2003.
404. Rizos AK, SPANDIDOS DA, Krambovitis E: Light scattering characterization of synthetic MUC-1 peptides and their behavior in dilute solution. International Journal of Molecular Medicine 12: 559-563, 2003.
405. Zafiropoulos A, Tsentelierou E, Billiri K and SPANDIDOS DA: Human herpes viruses in non-melanoma skin cancers. Cancer Letters 198: 77-81, 2003.
406. Zetterberg H, Zafiropoulos A, SPANDIDOS DA, Rymo L and Blennow K. Gene-gene interactions between fetal MTHFR 677C>T and transcobalamin 776C>G polymorphisms in human spontaneous abortion. Human Reproduction 18: 1948-1950, 2003.
407. Dialyna IA, Miyakis S, Georgatou N and SPANDIDOS DA: Genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes and lung cancer risk. Oncology Reports 10: 1829-1835, 2003.
408. Panutsopulos D, Zafiropoulos A, Krambovitis E, Kochiadakis GE, Igoumenidis NE and SPANDIDOS DA: Peripheral monocytes from diabetic patients with coronary artery disease display increased bFGF and VEGF mRNA expression. Journal of Translational Medicine 1: 6 (pp1-11), 2003.
409. Tsatsanis C, Zafiropoulos A and SPANDIDOS DA: Oncogenic kinases in cancer. Nature. Encyclopedia of the human genome, pp443-448, 2003.
410. Papadakis EN, Dokianakis DN and SPANDIDOS DA: Genetic analysis of H-ras intron-1 polymorphic and Variable Tandem Repeat regions in human breast cancer. International Journal of Biological Markers 18: 195-199, 2003.
411. Paraskakis E, Sourvinos G, Passam F, Tzanakis N, Tzortzaki EG, Zervou M, SPANDIDOS D, Siafakas NM: Microsatellite DNA instability and loss of heterozygosity in bronchial asthma. European Respiratory Journal 22: 951-955, 2003.
412. Mammas IN, Zafiropoulos A, Koumantakis E, Sifakis S and SPANDIDOS DA: Transcriptional activation of H- and N-ras oncogenes in human cervical cancer. Gynecologic Oncology 92: 941-948, 2004.
413. Krambovitis E, Zafiropoulos A, Baritaki S and SPANDIDOS DA: Simple electrostatic interaction mechanisms in the service of HIV-1 pathogenesis. Scandinavian Journal of Immunology 59: 231-234, 2004.
414. Dialyna I, Graham D, Razaee R, Blue CE, Stavrianeas N, Neisters HGM, SPANDIDOS DA and Blackbourn DJ. Anti-HHV-8/KSHV antibodies in infected individuals inhibit infection in vitro. AIDS 18: 1263-1270, 2004.
415. Baritaki S, Rizos E, Zafiropoulos A, Soufla G, Katsafouros K, Gourvas V and SPANDIDOS DA. Association between schizophrenia and DRD3 or HTR2 receptor gene variants. European Journal of Human Genetics 12: 535-541, 2004.
416. Zafiropoulos A, Crikas N, Passam AM and SPANDIDOS DA. Significant involvement of CCR2-64I and CXCL12-3A in the development of sporadic breast cancer. Journal of Medical Genetics 41: (S)e59, 2004.
417. Arvanitis DA, Lianos E, Soulitzis N, Delakas D and SPANDIDOS DA. Deregulation of p73 isoform equilibrium in benign prostate hyperplasia and prostate cancer. Oncology Reports 12: 1131-1137, 2004.
418. Tsatsanis C and SPANDIDOS DA. Oncogenic kinase signalling in human neoplasms. Annals of New York Academy of Sciences 1028: 168-175, 2004.
419. Carruba G, Cocciadiferro L, Bellavia V, Rizzo S, Tsatsanis C, SPANDIDOS D, Muti P, Smith C, Mehta P and Castagnetta L. Intercellular communication and human hepatocellular carcinoma. Annals of the New York Academy of Sciences 1028: 202-212, 2004.
420. SPANDIDOS DA. The cancer story. Cancer Biology and Therapy 3: 1184-1186, 2004.
421. Zafiropoulos A, Tsentelierou E, Linardakis M, Kafatos A and SPANDIDOS DA. Preferential loss of 5S and 28S RDNA genes in human adipose tissue during ageing. International Journal of Biochemistry and Cell Biology 37: 409-415, 2005.
422. Daly NL, Arvanitis DA, Fairley JA, Gomez-Roman N, Morton JP, Graham SV, SPANDIDOS DA and White RJ. Deregulation of RNA polymerase III transcription in cervical epithelium in response to high risk human papillomavirus. Oncogene 24: 880-888, 2005.
423. Arvanitis DA, Flouris GA and SPANDIDOS DA. Genomic rearrangements on VCAM1, SELE, APEG1 and AIF1 loci in atherosclerosis. Journal of Cellular and Molecular Medicine 9: 153-159, 2005.
424. Panutsopulos D, Papalambros E, Sigala F, Zafiropoulos A, Arvanitis DL and SPANDIDOS DA. Protein and mRNA expression levels of VEGF-A and TGF-§1 in different types of human coronary atherosclerotic lesions. International Journal of Molecular Medicine 15: 603-610, 2005.
425. Detorakis ET, Zafiropoulos A, Arvanitis DA and SPANDIDOS DA. Detection of point mutations at codon 12 of Ki-ras in ophthalmic pterygia. EYE 19: 210-214, 2005.
426. Soufla G, Sifakis S, Baritaki S, Zafiropoulos A, Koumantakis E and SPANDIDOS DA. VEGF, FGF2, TGFB1 and TGFBR1 mRNA expression levels correlate with the malignant transformation of the uterine cervix. Cancer Letters 221: 105-118, 2005.
427. Mammas LN, Zafiropoulos A and SPANDIDOS DA. Involvement of the ras genes in female genital tract cancer. International Journal of Oncology 26: 1241-1255, 2005.
428. Lyronis ID, Baritaki S, Bizakis I, Tsardi M and SPANDIDOS DA. Evaluation of human papilloma and Epstein-Barr viruses incidence in esophageal squamous cell carcinomas. International Journal of Biological Markers 20: 5-10, 2005
429. Soufla G, Baritaki S, Sifakis S, Zafiropoulos A and SPANDIDOS DA. Transcriptional inactivation of p53, Bax, Bcl-2 and mdm2 correlates with the malignant transformation of the uterine cervix. International Journal of Biological Markers 20: 18-27, 2005.
430. Baritaki S, Dittmar MT, SPANDIDOS DA and Krambovitis E. In vitro inhibition of R5 HIV-1 infectivity by X4 V3-derived synthetic peptides. International Journal of Molecular Medicine 16: 333-336, 2005.
431. Panutsopulos D, Arvanitis DL, Tsatsanis C, Papalambros E, Sigala F and SPANDIDOS DA. Expression of heregulin in human coronary atherosclerotic lesions. Journal of Vascular Research 42: 463-474, 2005.
432. Krambovitis E, Porichis F and SPANDIDOS DA. HIV-1 cell entry inhibitors; a new generation of antiretroviral drugs. Acta Pharmacologica Sinica 26: 1165-1173, 2005.
433. Passam AM, Zafiropoulos A, Miyakis S, Zagoraios Y, Stavrianeas NG, Krambovitis E and SPANDIDOS DA. CCR2-64I and CXCL12 3'A alleles confer a favorable prognosis to AIDS patients undergoing HAART therapy. Journal of Clinical Virology 34: 302-309, 2005.
434. Apostolakis S, Baritaki S, Krambovitis E and SPANDIDOS DA. Distribution of HIV/AIDS protective SDF-1, CCR5 and CCR2 gene variants within Cretan population. Journal of Clinical Virology 34: 310-314, 2005.
435. Mammas IN, Zafiropoulos A, Sifakis S, Sourvinos G and SPANDIDOS DA. Human papilloma virus (HPV) typing in relation to ras oncogene mRNA expression in HPV-associated human squamous cervical neoplasia. International Journal of Biological Markers 20: 257-263, 2005.
436. Guan M, Zhou X, Soulitzis N, SPANDIDOS DA and Popescu NC. Aberrant methylation and deacetylation of DLC-1 gene in prostate cancer; potential clinical applications. Clinical Cancer Research 12: 1412-1419, 2006.
437. Manolakopoulos S, Bethanis S, Elefsiniotis J, Karatapanis S, Triantos C, Sourvinos G, Touloumi G, Economou M, Vlachogiannakos J, SPANDIDOS D, Augerinos A and Tzourmakliotis D. Lamivudine monotherapy in HBeAg-negative chronic hepatitis B: Prediction of response-breakthrough and long-term clinical outcome. Alimentary Pharmacology and Therapeutics 23: 787-795, 2006.
438. Apostolakis S, Papadakis E, Krambovitis E and SPANDIDOS DA. Chemokines in vascular pathology. International Journal of Molecular Medicine 17: 691-701, 2006.
439. Soufla G, Porichis F, Sourvinos G, Vassilaros S and SPANDIDOS DA. Transcriptional deregulation of VEGF, FGF2, TGF-§1,Ź 2, 3 and cognate receptors in breast tumorigenesis. Cancer Letters 235: 100-113, 2006.
440. Amanatidou V, Sourvinos G, Apostolakis S, Tsilimigaki A and SPANDIDOS DA. T280M variation of the CX3C receptor gene is associated with increased risk for severe respiratory syneytial virus bronchiolitis. The Pediatric Infectious Disease Journal 25: 410-414, 2006.
441. Markaki E-A, Stiakaki E, Zafiropoulos A, Arvanitis DA, Katzilakis N, Dimitriou H, SPANDIDOS DA and Kalmanti M. Mutational analysis of the cell cycle inhibitor Kip1/p27 in childhood leukemia. Pediatric Blood and Cancer 47: 14-21, 2006.
442. Krambovitis E and SPANDIDOS DA. HIV-1 infection: is it time to reconsider our concepts? International Journal of Molecular Medicine 18: 3-8, 2006.
443. Soulitzis N, Karyotis I, Delakas D and SPANDIDOS DA. Expression analysis of peptide growth factors VEGF, FGF2, TGFB1, EGF and IGF1 in prostate cancer and benign prostatic hyperplasia. International Journal of Oncology 29: 305-314, 2006.
444. Mammas IN, Sourvinos G, Michael C and SPANDIDOS DA. Human papilloma virus in hyperplastic tonsillar and adenoid tissues in children. The Pediatric Infectious Disease Journal 25: 1158-1162, 2006.
445. Apostolakis S, Baritaki S, Kochiadakis GE, Igoumenidis NE, Panutsopoulos D and SPANDIDOS DA. Effects of polymorphisms in chemokine ligands and receptors on susceptibility to coronary artery disease. Thrombosis Research 119: 63-71, 2007.
446. Porichis F, Vlata Z, Hatzidakis G, SPANDIDOS DA and Krambovitis E. HIV-1 gp120/V3-derived epitopes promote activation-induced cell death to superantigen-stimulated CD4+/CD45RO+ T cells. Immunology Letters 108: 97-102, 2007.
447. Morikis D, Rizos AK, SPANDIDOS DA and Krambovitis E. Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: implications in the interaction with chemokine receptor CCR5. International Journal of Molecular Medicine 19: 343-351, 2007.
448. Tsoulogiannis IN and SPANDIDOS DA. Endocrinology in Ancient Sparta. HORMONES 6: 80-82, 2007.
449. Neonakis I, Gitti Z, Petinaki E, Maraki S and SPANDIDOS D. Evaluation of the GenoType MTBC assay for differentiating 120 clinical Mycobacterium tuberculosis complex isolates. European Journal of Clinical Microbiology and Infectious Diseases 26: 151-152, 2007.
450. Rizos AK, Baritaki S, Tsikalas I, Doetschman DC, SPANDIDOS DA and Krambovitis E. Biophysical characterization of V3-lipopeptide liposomes influencing HIV-1 infectivity. Biochemical Biophysical Research Communications 355: 963-969, 2007.
451. Panagiotakis SH, Soufla G, Baritaki S, Sourvinos G, Passam A, Zagoreos I, Stavrianeas N and SPANDIDOS DA. Concurrent CMV and EBV DNAemia is significantly correlated with a delay in the response to HAART in treatment naive HIV-1 positive patients. AIDS Research and Human Retroviruses 23: 10-18, 2007.
452. Batiraki S, Huerta-Yepez S, Neshan M, Sakai M, SPANDIDOS DA and Bonavida B. Genotoxic agents sensitize tumor prostate cells to TRAIL-mediated apoptosis through induction of DR5 expression resulted by inhibition of YY1/NF-kB pathway. Molecular Cancer Therapeutics 6: 1387-1399, 2007.
453. Baritaki S, Apostolakis S, Kanellou P, Dimanche-Boitel MT, SPANDIDOS DA and Bonavida B. Reservae of tumor resistance to apoptotic stimuli by alteration of membrane fluidity: Therapeutic implications. Advances in Cancer Research 98: 149-190, 2007.
454. Symvoulakis EK, Zaravinos A, Panutsopulos D, Zoras O, Papalambros E, Sigala F and SPANDIDOS DA. Highly conserved sequence of exon 15 BRAF gene and K-ras codon 12 mutation among Greek patients with colorectal cancer. The Inter-national Journal of Biological Markers 22: 12-18, 2007.
455. Baritaki S, Sifakis S, Yepez SH, Neonakis IK, Soufla G, Bonavida B and SPANDIDOS DA. Overexpression of VEGF and TGF-beta1 mRNA in Pap smears correlates with progression of cervical intraepithelial neoplasia to cancer: Implication of YY1 in cervical tumorigenesis and HPV infection. International Journal of Oncology 31: 69-79, 2007.
456. Tsoulogiannis IN and SPANDIDOS DA. Eclectics and breast cancer. Journal of B.U.ON. 12: 183-188, 2007.
457. Signorelli SS, Mazzarino MC, SPANDIDOS DA and Malaponte G. Proinflammatory circulating molecules in peripheral arterial disease. International Journal of Molecular Medicine 20: 279-286, 2007.
458. Neonakis IK, Gitti Z, Baritaki M, Kourbeti IS, Baritaki S, Petinaki E, Maraki S, Krambovitis E and SPANDIDOS DA. Resistance status of Mycobacterium tuberculosis on the island of Crete, Greece. European Journal of Clinical Microbiology and Infectious Diseases 26: 607-609, 2007.
459. Lee JY, Yepez SH, Vega M, Baritaki S, SPANDIDOS DA and Bonavida B. The NO TRAIL to YES TRAIL in cancer therapy. International Journal of Oncology 31: 685-691, 2007.
460. Sourvinos G, Tavalai N, Berndi A, SPANDIDOS DA and Stamminger T. Recruitment of human cytomegalovirus immediate early 2 protein onto parental viral genomes in association with ND10 in live infected cells. Journal of Virology 81: 10123-10136, 2007.
461. Passam AM, Sourvinos G, Krambovitis E, Miyakis S, Stavrianeas N, Zagoreos I and SPANDIDOS DA. Polymorphisms of CX3CR1 and CXCR6 receptors in relation to HAART therapy of HIV-1 patients. AIDS Research and Human Retroviruses 23: 1026-1032, 2007.
462. SPANDIDOS DA. Oncogenes and tumor-suppressor genes as paradigms in oncogenesis. Journal of BUON 12 (Suppl 1): S9-S12, 2007.
463. Baritaki S, Katsman A, Chatterjee D, Yeung KC, SPANDIDOS DA and Bonavida B. Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation. Journal of Immunology 179: 5441-5453, 2007.
464. Zaravinos A, Bizakis J, Soufla G, Sourvinos G and SPANDIDOS DA. Mutations and differential expression of the ras family genes in human nasal polyposis. International Journal of Oncology 31: 1051-1059, 2007.
465. Neonakis IK, Gitti Z, Kourbeti IS, Michelaki H, Baritaki M, Alevraki G, Papadomanolaki E, Tsafaraki E, Tsouri A, Baritaki S, Krambovitis E and SPANDIDOS DA. Mycobacterial species diversity at a general hospital in the island of Crete: First detection of Mycobacterium lentiflavum in Greece. Scandinavian Journal of Infectious Diseases 30: 875-879, 2007.
466. Vageli D, Sourvinos G, Ioannou M, Koukoulis G and SPANDIDOS DA. High risk human papillomavirus (HPV) in parotid lesions. International Journal of Biological Markers 22: 239-244, 2007.
467. Balis V, Sourvinos G, Soulitzis N, Giannikaki E, Sofras F and SPANDIDOS DA. Detection of BK virus and human papilloma virus in human prostate malignancies. International Journal of Biological Markers 22: 245-251, 2007.
468. Apostolakis S, Krambovitis E, Vlata C, Kochiadakis GE and SPANDIDOS DA. CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: Impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thrombosis Research 121: 387-395, 2007.
469. Zaravinos A, Soufla G, Bizakis J and SPANDIDOS DA. Expression analysis of VEGFA, FGF2, TGF§1, EGF and IGF1 in human nasal polyposis. Oncology Reports 19: 385-391, 2008.
470. Porichis F, Morou A, Baritaki S, SPANDIDOS DA and Krambovitis E. Activation-induced cell death signaling in CD4+ T cells by staphylococcal enterotoxin A. Toxicology Letters 176: 77-84, 2008.
471. Amanatidou V, Sourvinos G, Apostolakis S, Neonaki P, Tsilimigaki A, Krambovitis E and SPANDIDOS DA. RANTES promoter gene polymorphisms and susceptibility to severe Respiratory Syncytial Virus-induced bronchiolitis. The Pediatric Infectious Disease Journal 27: 38-42, 2008.
472. Soufla G, Sifakis S and SPANDIDOS DA. FGF-2 transcript levels are positively correlated with EGF and IGF-1 in the malignant endometrium. Cancer Letters 259: 146-155, 2008.

Last updated: 5 May 2008
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