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CURRICULUM VITAE

Demetrios A. Spandidos

Date and Place of Birth:
April 13th, 1947. Agios Constantinos, Sparta, Greece

Education:

  • B.Sc. in Chemistry, November 1971, Aristotelion University of Thesaloniki, Greece
  • Ph.D. in Biochemistry, January, 1976, McGill University, Montreal, Canada ,Title of Ph.D. Thesis: Genetics and Transcription of Reovirus
  • M.R.C Path. November, 1988.Royal College of Pathologists, London, UK
  • D.Sc. in Genetics, July 1989. University of Glasgow, Scotland, UK, Title of D.Sc. Thesis: Studies on the role of ras gene in carcinogenesis
  • F.R.S.H. June 1994. The Royal Society of Health, London, UK
  • F.R.C.Path January 1997. The Royal College of Pathologists, London, UK
  • Specialty in Clinical Chemistry, 1998. Ministry of Health, Greece
  • FASA, 2005. The American Society of Angiology

Marital Status:
Married to Dr. Panayota D. Krempeniou (Ph.D. in Law, University of Glasgow, UK) in 1976. Two children, born in 1977 (daughter, Ph.D. in Molecular Biology, Cambridge, UK) and 1981 (son, MSc in Molecular Biology, University of Edinburgh, UK)

Citizenship:
Greek

Professional Experience :

1989 - Present:    Professor of Virology, Medical School, University of Crete, Heraklion, Greece

1990 - Present:    Director, Laboratory of Clinical Virology, University Hospital, Heraklion, Greece

2006 - Present:    Laboratories of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital, Heraklion, Greece

1988 - 1998:    Director, Laboratory of Molecular Oncology and Biotechnology, Institute of Biological Research and Biotechnology, The National Hellenic Research Foundation, Athens, Greece

1981 - 1988:    Member of the Senior Scientific Staff, Beatson Institute for Cancer Research, Glasgow, Scotland, UK

1985 - 1987:    Head, Virology Programme, Hellenic Institute Pasteur, Athens, Greece

1985 - 1987:    Visiting Scientist and Guest lecturer "Genes and Cancer" course for medical, graduate and undergraduate students, Department of Pediatrics, Medical School, University of California, San Diego, USA
(Feb-March
each year)

1979 - 1981:    Centennial Fellow (MRC Canada), Beatson Institute for Cancer Research, Glasgow, Scotland, UK

1979:    Director, Laboratory of Biochemistry, Medical Center of Athens Hospital, Athens, Greece

1978 - 1979:    Epimelitis (Assistant Professor), Laboratory of Biochemical and Biological Research, Hellenic Anticancer Institute, Athens, Greece

1976 - 1978:    Post-doctoral Fellow (MRC Canada), Department of Medical Genetics, University of Toronto, Toronto, Canada

July 1976:    Cold Spring Harbor Laboratory, USA. Advanced Bacterial Genetics Course, including the recombinant DNA technology

1972 - 1976:    Teaching Assistant, Department of Biochemistry, McGill University, Montreal, Canada

1970 - 1971:    Research Assistant, Laboratory of Virology and Tissue Culture, Theagenion Cancer Institute, Thessaloniki, Greece

Additional Responsibilities:
Editor:
A. Journals

  • International Journal of Oncology (since 1992) (included in Science Citation Index and Index Medicus)
  • Oncology Reports (since 1994) (included in Science Citation Index and Index Medicus)
  • International Journal of Molecular Medicine (since 1998) (included in Science Citation Index and Index Medicus)
  • Molecular Medicine Reports (since 2008)
  • Anticancer Research (Annual Special Issues from 1985 to 1990)

B. Books in English

  • Current Perspectives on Molecular and Cellular Oncology, JAI Press Ltd, London, UK. Volume 1. Part A pp1-318, Part B pp1-332, 1992
  • Ras oncogenes, by D.A. Spandidos. Plenum Press. New York and London, pp1-323, 1989
  • The super-family of ras related genes, by D.A. Spandidos, Plenum Press, New York and London, pp1-337, 1992

C. Books in Greek
(Approved by the Ministry of Education for the Greek Universities)

  • Virology by D.A. Spandidos, Litsas Press, Athens pp1-260, 1991
  • Safety Manual for Universities and Research Centers by D.A. Spandidos, Litsas Press, Athens pp1-160, 1991
  • Molecular and Cellular Oncology by D.A. Spandidos, Litsas Press, Athens, pp1-448, 1992
  • Clinical Virology by D.A. Spandidos, Lychnia Press, Athens, pp1-364, 1998
  • Molecular Oncology by D.A. Spandidos, Lychnia Press, Athens, pp1-521, 2000

C. Books in Greek/English

  • Asclepius Sanctuaries in Laconia, pp1-75, 2005

Member of the Editorial Boards:

  • Anticancer Research (1985-1993)
  • In vivo (1988-1993)
  • European Journal of Cancer-Oral Oncology (since 1992-2007)
  • Molecular and Cellular Differentiation (1993-1995)
  • Cancer Molecular Biology (1994-2000)
  • Pathology Oncology Research (since 1995)
  • The International Journal of Biological Markers (since 1995)
  • Minerva Biotechnologica (since 1996)
  • Journal of Balkan Union of Oncology (since 1996)
  • Journal of Cellular and Molecular Medicine (2001-2006)
  • Austral-Asian Journal of Cancer (since 2003)
  • Current Cancer Therapy Reviews (since 2004)
  • Acta Pharmacologica Sinica (since 2005)
  • The Open Neuroscience Journal (since 2007)
  • Romanian Archives of Microbiology and Immunology (since 2007)
  • The Open Cancer Journal (since 2007)
  • The Open Neurology Journal (since 2007)
  • The Open Dermatology Journal (since 2007)
  • Journal of Taibah University Medical Sciences (since 2007)

Meetings Organizer:

1.    Chairman, Organizing Committee of the 35th Meeting of the European Tissue Culture Society (ETCS), Athens, Greece, 1987

2.    Chairman, Organizing Committee and the 25th Meeting of the Cell, Tissue and Organ Culture Study Group (CTOC) Athens, Greece, 1987

3.    Director, NATO Advanced Research Workshop on 'Ras oncogenes', Athens, Greece, 1988

4.    Chairman, Organizing Committee of the European Association for Cancer Research Sponsored Spring Symposium on 'Oncogenes and Onco-supressor Genes', Athens, Greece, 1989

5.    Director, FEBS Advanced Lecture Course on 'The Role of Oncogenes and Biological Response Modifiers in Tumor Invasion and Metastasis'. Athens, Greece, 1989

6.    Chairman, Organizing Committee of the International Conference on 'Cell Differentiation/Oncogenesis'. Athens, Greece, 1990

7.    Director, NATO Advanced Research Workshop on 'The Super-family of ras Related Genes', Agia Pelagia, Crete, Greece, 1991

8.    Chairman, Organizing Committee of the International Seminar Course entitled 'Breast Cancer: Therapeutic Strategy and Molecular Biology'. Agia Pelagia, Crete, Greece, 1991

9.    Chairman, Organizing Committee of the International Seminar Course entitled 'Colorectal Cancer: Therapeutic Strategy and Molecular Biology'. Vouliagmeni, Athens, Greece, 1992

10.  Chairman, Organizing Committe of the '1st World Congress on Advances in Oncology', Athens, Greece, 1995

11.  Chairman, Organizing Committee of the 'Oncology 1996' Conference, Island of Kos, Greece, 1996

12.  Chairman, Organizing Committee of the '2nd World Congress on Advances in Oncology', Athens, Greece, 1997

13.  Chairman, Organizing Committee of the '3rd World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 1998

14.  Chairman, Organizing Committee of the '1st International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 1998

15.  Chairman, Organizing Committee of the 'Seminar on Cancer Research', of the Balkan School of Oncology, Athens, Greece, 1998

16.  Chairman, Organizing Committee of the '4th World Congress on Advances in Oncology', Vouliagmeni, Athens, Greece, 1999

17.  Chairman, Organizing Committee of the '2nd International Symposium on Molecular Medicine', Vouliagmeni, Athens, Greece, 1999

18.  Chairman, Organizing Committee of the '5th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2000

19.  Chairman, Organizing Committee of the '3rd International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 2000

20.  Chairman, Organizing Committee of the '6th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2001

21.  Chairman, Organizing Committee of the '4th International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 2001

22.  Chairman, Organizing Committee of the '7th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2002

23.  Chairman, Organizing Committee of the '5th International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 2002

24.  Chairman, Organizing Committee of the '8th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2003

25.  Chairman, Organizing Committee of the '6th International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 2003

26.  Chairman, Organizing Committee of the '9th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2004

27.  Chairman, Organizing Committee of the '7th International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 2004

28.  Chairman, Organizing Committee of the '10th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2005

29.  Chairman, Organizing Committee of the '8th International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 2005

30.  Chairman, Organizing Committee of the '11th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2006

31.  Chairman, Organizing Committee of the '9th International Symposium on Molecular Medicine',Hersonissos, Crete, Greece, 2006

32.  Chairman, Organizing Committee of the '12th World Congress on Advances in Oncology', Hersonissos, Crete, Greece, 2007

33.  Chairman, Organizing Committee of the '10th International Symposium on Molecular Medicine', Hersonissos, Crete, Greece, 2007

Advisory and Administrative Responsibilities:

  • Member of the Advisory Board, Institute of Developmental Neuroscience and Aging (1986-1990)
  • Member of the Board of Governors and Nomination Committee of the International Association for Breast Cancer Research (1991-1998)
  • Member of the Scientific Board of the Roy Castle International Center for Lung Cancer Research, Liverpool, UK (since 1996-2004)
  • Member of the Board of Governors of Euroscience (1997-2000)
  • Director of the section of Laboratory Medicine, Medical School, University of Crete, Heraklion, Greece
  • Member of the Board of Directors, Medical School, University of Crete, Heraklion, Greece
  • Member of the Committee of Graduate Studies, Medical School, University of Crete, Heraklion, Greece

Honors/Awards:

  • Honorary Member of the Hellenic Society of Mastology, Athens, Greece (1987)
  • Corresponding Member of the Academia National de Medicina de Buenos Aires, Buenos Aires, Argentina (1989)
  • Honorary Member of the Hellenic Society for Lung Cancer, Pireas, Greece (1990)
  • Doctor Honoris Causa of Ś‚Carol DavilaŚé University of Medicine and Pharmacy, Bucharest, Romania (2002)
  • Honorary Member of the Hellenic Society for Toxicology, Greece (2002)
  • Doctor Honoris Causa of Ś‚Iuliu HatieganuŚé University of Medicine and Pharmacy, Cluj-Napoca, Romania (2004)
  • Visiting Professor, University of Catania, Italy (2005)
  • Honorary Member of the Balkan Union of Oncology (2007)

Publications (By January 2008)
Professor D.A. Spandidos has authored more than 470 publications in English in 130 different international journals and more than 50 publications in Greek journals. His work has received over 7500 citations. His major findings have been discussed in the journals Nature, Science, New Scientist and The Economist among others.

Communications (By January 2008)
Professor D.A. Spandidos has participated with more than 750 communications and invited talks in International Conferences.

Ph.D. Supervisor:
More than 60 graduate students have obtained their Ph.D. degree in Greece under the supervision of Professor D.A. Spandidos and most of them are pursuing careers abroad in leading institutions in the field of cancer research as shown by work published in top biomedical journals.

Research Achievements:
Among his most significant work is included the discovery of avian reovirus (DA Spandidos and AF Graham, J Virol 19: 977, 1976 - more than 65 citations), the discovery of cellular oncogenes by gene transfer (DA Spandidos and L Siminovitch, Cell 12: 675, 1977 and DA Spandidos and L Siminovitch, Nature 271: 259, 1978), the transfer of human globin genes to hemopoietic cells (DA Spandidos and J Paul, EMBO J 1: 15, 1982 - more than 65 citations), the involvement of ras genes in colon tumours (DA Spandidos and IB Kerr, Br J Cancer 49: 681, 1984 - more than 210 citations), the mechanism of transformation by ras genes (DA Spandidos and NM Wilkie, Nature 310: 469, 1984 - more than 510 citations), the role of ras and myc genes in apoptosis (AH Wyllie, KA Rose, RG Morris, CM Steel, E Foster and DA Spandidos, Br J Cancer 56: 251, 1987 - more than 190 citations) and the involvement of p53 in head and neck carcinomas (JK Field, DA Spandidos, A Malliri, JR Gosney, M Yiagnisis and PM Stell, Br J Cancer 64: 573, 1991 - more than 250 citations) among others.

Last updated: 5 May 2008
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